Moxibustion Improves Ovarian Function Based on the Regulation of the Androgen Balance

    Xiaobin Jin, Jie Cheng, Jie Shen, Xing Lv, Qian Li, Yiming Mu, Hua Bai, Yan Liu, Yun Xia
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    Studysummary This study suggested that moxibustion treatment before or at the early stage of diminished ovarian reserve in rats may improve ovarian function by modulating androgen balance, though its effects differ across intervention timings.
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    The study "Moxibustion improves ovarian function based on the regulation of the androgen balance" found that moxibustion treatment in a rat model of diminished ovarian reserve (DOR) significantly improved ovarian function by regulating androgen levels. Thirty-two rats were divided into four groups and treated with moxibustion daily for 20 days. Results showed increased AMH and DHT levels, decreased FSH, T, and DHEA levels, and increased AR content in the ovary. Moxibustion reduced atretic follicles, increased mature follicular cells, and normalized disrupted serum levels of AMH, FSH, and E2. The study suggests moxibustion could be a beneficial non-pharmacological treatment for ovarian dysfunction, with different effects observed between pre-disease and early-disease interventions. Further research is needed to determine optimal treatment duration and timing.
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