Therapeutic Effect of Impatiens Balsamina, Lawsonia Inermis L., and Henna on Androgenetic Alopecia in Mice

November 2019 in “ PubMed ”

Yushi Zheng, Yongxuan Hu, Kangxing Liu, Yan Lu, Yanqing Hu, Xianyi Zhou

Impatiens balsamina Lawsonia inermis L. Henna androgenetic alopecia minoxidil testosterone propionate dihydrotestosterone C57BL/6 mice Rogaine testosterone DHT

Studysummary This study found that Henna had the most pronounced effect on hair growth in a mouse model of androgenetic alopecia, possibly by reducing local androgen content.

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The study investigated the therapeutic effects of Impatiens balsamina, Lawsonia inermis L., and Henna on androgenetic alopecia in C57BL/6 mice. Forty-eight male mice were divided into six groups, including a control group and a minoxidil group. The mice were treated with testosterone propionate to induce alopecia and then received topical applications of the respective treatments for 35 days. Results showed that all tested drugs promoted hair growth, with Henna showing the most significant effect, resulting in the highest hair density and a color change in the skin. Impatiens balsamina and Henna significantly reduced testosterone and dihydrotestosterone levels in the skin, suggesting their therapeutic effect might be due to lowering local androgen content.

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