Cornu Cervi Pantotrichum Pharmacopuncture Solution Facilitates Hair Growth in C57BL/6 Mice

June 2016 in “ Journal of Pharmacopuncture ”

Seon-Yong Lee, Dong Hoon Lee, Kang Kwon, Chang-Hyun Lee, Hyun Jong Shin, Jai-Eun Kim, Ki-Tae Ha, Hyein Jeong, Hyung-Sik Seo

Cornu cervi pantotrichum pharmacopuncture hair growth dermal papilla hair shaft hair thickness hair follicles bromodeoxyuridine BrdU proliferating cell nuclear antigen PCNA fibroblast growth factor FGF-7 alopecia CCPPS hair loss

Studysummary This study found that Cornu cervi pantotrichum pharmacopuncture solution significantly promoted hair growth in mice by enhancing hair follicular cell proliferation and up-regulating FGF-7 expression. Our plain-language summary of this paper — not a Tressless recommendation.

The study from 2016 examined the impact of Cornu cervi pantotrichum pharmacopuncture solution (CCPPS) on hair growth in C57BL/6 mice, with each experimental group consisting of four mice. The mice received topical CCPPS treatments daily for 15 days after hair depilation. The findings indicated that CCPPS significantly promoted hair growth, as evidenced by the enlargement of the dermal papilla, elongation of the hair shaft, and increased hair thickness. Histological analysis showed increased cellular proliferation within hair follicles, as marked by elevated levels of bromodeoxyuridine (BrdU) and proliferating cell nuclear antigen (PCNA). Furthermore, CCPPS enhanced the expression of fibroblast growth factor (FGF)-7, which is essential for hair follicle development. The study concluded that CCPPS could be a potential alternative treatment for alopecia due to its ability to stimulate hair follicular cell proliferation and upregulate FGF-7.

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