TLDR A genetic mutation in the LIPH gene causes hair loss and growth defects.
The study conducted by Anastasiya Kazantseva and colleagues in 2006 identified a genetic defect in the phospholipase gene LIPH as a cause of human hair growth deficiency. The research linked mutations in the LIPH gene to conditions such as hypotrichosis and woolly hair, which are characterized by sparse and abnormal hair growth. This discovery provided significant insights into the genetic basis of hair growth disorders and highlighted the importance of the LIPH gene in normal hair follicle function. The findings were supported by genetic analysis and were crucial for understanding the molecular mechanisms underlying hair growth deficiencies.
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February 2014 in “PloS one” LIPH mutations in Japan cause varying degrees of hair loss and woolly hair.
