Human Hair Growth Deficiency Is Linked to a Genetic Defect in the Phospholipase Gene LIPH

The study conducted by Anastasiya Kazantseva and colleagues in 2006 identified a genetic defect in the phospholipase gene LIPH as a cause of human hair growth deficiency. The research linked mutations in the LIPH gene to conditions such as hypotrichosis and woolly hair, which are characterized by sparse and abnormal hair growth. This discovery provided significant insights into the genetic basis of hair growth disorders and highlighted the importance of the LIPH gene in normal hair follicle function. The findings were supported by genetic analysis and were crucial for understanding the molecular mechanisms underlying hair growth deficiencies.