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research Human Hair Growth Deficiency Is Linked to a Genetic Defect in the Phospholipase Gene LIPH

194 citations , November 2006 in “Science”

This study identified a gene mutation in the LIPH gene associated with inherited hair loss and hair growth defects in certain populations, suggesting lipase H plays a role in hair development.

research Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition

76 citations , March 2005 in “Journal of Molecular Medicine”

This study found that premature hair loss due to stress does not occur in NK-1 receptor knockout or mast cell deficient mice, suggesting a key role for neurokinin substance P and mast cell interaction in stress-related hair follicle changes.

research Deficiency of Crif1 in hair follicle stem cells retards hair growth cycle in adult mice

10 citations , April 2020 in “PloS one”

This study found that mitochondrial dysfunction due to Crif1 deficiency in hair follicle stem cells significantly slows the hair growth cycle in adult mice but does not impact the maintenance of HFSC populations.

research Effects of Long Term Zinc Deficiency on Feed Utilization, Reproductive Characteristics, and Hair Growth in the Sexually Mature Male Goat

40 citations , January 1973 in “Journal of Dairy Science”

This study found that zinc deficiency in goats led to lower plasma zinc levels, decreased growth rate, smaller testicles, reduced libido, and was associated with higher mortality compared to control goats.

research MYB30 and ETHYLENE INSENEITIVE3 antagonistically regulate root hair growth and phosphorus uptake under phosphate deficiency in Arabidopsis

16 citations , April 2021 in “Plant Signaling & Behavior”

This study found that in Arabidopsis, the MYB30-EIN3 module plays a role in adapting root hair development to phosphate deficiency, potentially enhancing phosphate uptake from soil.

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Community Join

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community How much hair growth potential can be lost due to lifestyle factors?

in Treatment 9 upvotes 1 year ago

Lifestyle factors like diet, stress, and nutrient deficiencies can impact hair regrowth, but their effects vary among individuals. Treatments mentioned include finasteride, dutasteride, and minoxidil.

community Ranking the best treatments for hair growth

in Research/Science 3 upvotes 6 months ago

Effective hair growth treatments include finasteride, minoxidil, dutasteride, and hair transplants, with additional options like microneedling, low-level laser therapy, and PRP showing some benefits. Newer treatments such as GHK-Cu peptides and ketoconazole shampoo are promising, while others like saw palmetto and biotin are less effective unless deficiencies exist.

community 26F Thinner hair due to vitamin deficiencies?

13 upvotes 2 years ago

A female user with chronic anemia and vitamin deficiencies is experiencing finer, straighter hair and seeks recommendations for scalp products to improve circulation and prevent potential hair thinning. She is considering growth oils but is unsure of their effectiveness.

community Vitamin E and K deficiency (F,25)

in Research/Science 3 upvotes 4 months ago

Vitamin E and K deficiencies due to exocrine pancreatic insufficiency may affect hair growth. A scalp biopsy is recommended to check for autoimmune-related hair loss.

community Is this "Hair growth complex" pill from sons anything?

28 upvotes 9 months ago

The conversation discusses the effectiveness of a "Hair growth complex" pill, with skepticism about its ingredients like saw palmetto and anagain. Users suggest saw palmetto may help slightly with DHT-related hair loss, but it's less effective than finasteride or dutasteride.

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Learn

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learn Vitamin B12

Can topical products containing Vitamin B12 improve scalp health and hair growth? Topical Vitamin B12 may not significantly improve hair growth unless there's a deficiency.

learn vitamin b2

Should Vitamin B2 be combined with other B vitamins for better hair growth results? Combining Vitamin B2 with other B vitamins may enhance hair growth if deficiencies exist.

learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.
Is there a difference between taking folic acid supplements and using folic acid in topical hair products? Oral folic acid uses the body's normal absorption route and can correct a measured deficiency, but no published trial shows it treats hair loss; topical folic acid has no human evidence for hair growth and struggles to cross the skin barrier at all.

learn Stem Cell Factor

learn Selenium

Is Selenium more effective when taken orally or applied topically in shampoos or serums? The two are not interchangeable and the evidence points the other way from the common assumption: topical selenium disulfide shampoo has clinical trial support for dandruff and seborrheic dermatitis, while oral selenium supplements have no reliable evidence for hair growth in people who are not deficient, and excess intake is a recognised cause of hair loss.

learn Biotin

supplement to help with hair texture and quality

learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas