Effects of Melatonin Supplementation on Hormonal, Inflammatory, Genetic, and Oxidative Stress Parameters in Women With Polycystic Ovary Syndrome

    May 2019 in “ Frontiers in Endocrinology ”
    Mehri Jamilian, Fatemeh Foroozanfard, Naghmeh Mirhosseini … Zatollah Asemi
    Studysummary This study found that administering melatonin for 12 weeks to women with PCOS significantly reduced hirsutism, testosterone, and inflammation markers, while enhancing antioxidant levels compared to a placebo.
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    Research cited in this study 4

    1. Interventions for Hirsutism Excluding Laser and Photoepilation Therapy Alone: Abridged Cochrane Systematic Review Including GRADE Assessments British journal of dermatology/British journal of dermatology, Supplement · 2016
    2. Endocrine and Reproductive Effects of Polycystic Ovarian Syndrome Obstetrics and Gynecology Clinics of North America · 2014
    3. Protective Effects of Melatonin Against Metabolic and Reproductive Disturbances in Polycystic Ovary Syndrome in Rats Journal of Pharmacy and Pharmacology · 2014
    4. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome Fertility and Sterility · 2004

    Related research 1

    1. Hirsutism Scoring in Polycystic Ovary Syndrome: Concordance Between Clinicians' and Patients' Self-Scoring Fertility and Sterility · 2010