Immune Mechanisms Associated With Sex-Based Differences In Severe COVID-19 Clinical Outcomes

    March 2022 in “ Biology of Sex Differences ”
    Cosby G. Arnold, Anne M. Libby, Alexis Vest … Andrew A. Monte
    Studysummary This review examines biological reasons for sex-based differences in COVID-19 outcomes, noting that females exhibit stronger immune responses, potentially explaining lower severity and mortality compared to males.
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    Research cited in this study 4

    1. Sex- Or Gender-Specific Differences In The Clinical Presentation, Outcome, And Treatment Of SARS-CoV-2 Clinical Therapeutics · 2021
    2. Sex Differences in COVID-19: The Role of Androgens in Disease Severity and Progression Endocrine · 2020
    3. Androgenetic Alopecia Present in the Majority of Patients Hospitalized with COVID-19: The 'Gabrin Sign' Journal of The American Academy of Dermatology · 2020
    4. A Preliminary Observation: Male Pattern Hair Loss Among Hospitalized COVID-19 Patients in Spain – A Potential Clue to the Role of Androgens in COVID-19 Severity Journal of Cosmetic Dermatology · 2020