Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the progress in research on topical formulations for treating alopecia, highlighting potential advantages of advanced formulation technologies but reporting no new clinical results.

This study examined the latest advances in synthetic biology for increasing microbial production of sesquiterpenol compounds, highlighting innovative strategies to overcome challenges such as low yields and terpenoid-related toxicity, which hinder industrial-scale applications.

This study evaluated Humulus lupulus (hops) extract in cosmetic formulations and found it to maintain antioxidant and anti-irritant properties, reducing erythema by 10% after three weeks of use, supporting its potential for skin health improvement in plant-based cosmetics.

This study examined the factors contributing to gray hair, such as genetics and lifestyle, and found that while graying correlates with some health conditions, it is primarily a physiological process rather than a pathological one.

This study found that Clinopodium bolivianum essential oil, particularly in combing cream, demonstrated notable antioxidant activity, with potential applications as a natural antioxidant in cosmetic formulations.

In this study, the researchers developed minoxidil cubosomes using nanotechnology, which improved drug penetration in the skin, showed greater hair growth efficacy, and reduced adverse skin reactions compared to traditional minoxidil solutions.

This review highlights that vitexin, a natural flavonoid derived from plants like mung bean, modulates critical cellular processes involved in cancer progression, suggesting its potential as a multi-target anticancer treatment in preclinical studies.

In this study using ex vivo porcine ear skin, researchers found that standard nail varnish applied gently creates effective follicular closures, preventing penetration of certain substances like fluorescein sodium salt and caffeine into hair follicles, whereas solvent-free varnish and rapid application techniques were less effective.

This study found that idebenone-loaded nanoparticles (IB@NPs) improved stability, antioxidant activity, and wound healing capacity in vitro, suggesting potential applications in cosmetic and pharmaceutical fields.

This study optimized the reaction conditions for the stereoselective hydrogenation of a compound used in manufacturing finasteride and dutasteride, improving the selectivity for the desired isomer.

This study comparatively evaluated different extraction techniques for Schinus terebinthifolius Raddi leaf extracts and found that conventional extraction with ethanol yielded the highest antioxidant activity and beneficial effects on skin cell viability, supporting its potential use in sustainable cosmeceutical formulations targeting skin aging.

This systematic review found that while green solvent- and natural excipient-based semisolid formulations often show promising efficacy and safety compared to conventional options, the evidence does not currently establish superior stability, highlighting a need for further research on long-term formulation quality.

This study established a sensitive and reproducible method for determining the levels of four organic solvents in finasteride raw materials, meeting the requirements of the Chinese Pharmacopeia.

This study investigated the solubility of minoxidil in various solvent mixtures and applied multiple models to understand solute-solvent interactions and energy dynamics.

This study established a reliable method for determining residual solvents in Finasteride using gas chromatography.

This study found that endophytic bacteria isolated from Leea indica leaves showed high antioxidant activity, suggesting they could be a novel source of natural antioxidants.

This study described a novel three-dimensional-printed microneedle system designed for improved transdermal delivery of minoxidil to treat hair loss, demonstrating effective hair regrowth and safety in a mouse model while allowing sustainable needle base recovery.

This study developed a novel, 3D-printed dissolving microneedle system for delivering minoxidil to treat hair loss, which showed pH-triggered drug release and enhanced hair regrowth in an alopecia mouse model, offering a potentially sustainable and safe transdermal therapy option.

In this study, researchers developed a delivery system using a deep eutectic solvent to improve hydroxytyrosol absorption for hair regrowth, achieving over threefold greater skin penetration compared to aqueous solutions and demonstrating its effectiveness and biocompatibility in hair regrowth and ROS-scavenging tests.

Using a special solvent can make Cacumen Platycladi essential oil more effective for treating hair loss.

This study investigated the morphology and growth mechanisms of spherical crystal aggregates of minoxidil in various alcoholic solvents, finding that a n-butanol–ethyl acetate mixture produces unique spherulite aggregates with improved powder characteristics.

In this study, the NADES extract of mangkokan leaves (Polyscias scutellaria) demonstrated antibacterial activity against Escherichia coli and Staphylococcus aureus, with a total flavonoid content measured at 4.944 mgEQ/gSimplisia using the disc diffusion method.

This study examined the stability of two 5α-reductase inhibitors in Tectona grandis extracts, finding that they are more stable in acidic environments and degrade rapidly under heat and light unless protected, suggesting the need for careful storage when developing anti-hair loss medications.

This study found that using headspace capillary gas chromatography effectively determined the levels of residual organic solvents, including chloroform and dichloromethane, in finasteride with good separation and detection limits.

This study found that methanol is more effective than isopropanol at removing external cortisol from grizzly bear hair and suggests that the choice of solvent can influence hair cortisol concentration results.

This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.

This review describes deep eutectic solvents as a green alternative to toxic solvents in extracting bioactive compounds, highlighting their sustainability, production from natural ingredients, and beneficial properties for pharmaceutical applications.

This study characterized bioactive compounds in extracts from six Kalimantan herbal plants, confirming traditional medicinal uses with findings such as triterpenoids and several potent compounds with antimicrobial and cardiovascular benefits, laying groundwork for potential therapeutic applications and conservation efforts.

This study found that hair follicles contribute significantly to caffeine absorption shortly after topical application, with a faster absorption rate compared to the stratum corneum.

This thesis explored how stratum corneum barrier disruption and pH-sensitive nanoparticles influence drug penetration and release in skin models, highlighting potential applications for treating atopic dermatitis.