Recent Advances in Multiple Strategies for the Biosynthesis of Sesquiterpenols

The document discusses recent advances in the biosynthesis of sesquiterpenols, which are natural compounds with significant biological activities and applications in various industries. Despite their potential, challenges such as low yields and high production costs hinder their industrial-scale production. The paper highlights the role of synthetic biology in overcoming these challenges through innovative microbial production strategies. Key areas of focus include adaptive sesquiterpenol synthase screening, synthesis pathway regulation, intracellular compartmentalized expression, and managing terpenoid-related toxicity. The document also addresses critical challenges and future directions for enhancing sesquiterpenol biosynthesis research.