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In this study, forming inclusion complexes of Finasteride and poly (ethylene glycol) resulted in significantly improved solubility and dissolution rates, suggesting a promising new solid form for enhanced drug release.

In this study, CoQ10 and selenium nanoparticles showed potential to alleviate hyperlipidemia and simvastatin-induced side effects in rats, but a triple combination with simvastatin caused intense liver and muscle damage.

This article reviews self-assembled nanoparticles, highlighting their promising role in drug delivery systems but noting the need for further research on stability and large-scale industrial application; it reports no new clinical findings.

In this study, researchers developed topical tofacitinib-loaded cationic lipid nanoparticles, which improved absorption and targeted hair follicles in an ex vivo pig ear model, showing promise in treating alopecia areata by reducing symptoms through the JAK/STAT pathway.

This review discusses the potential of biomimetic synthetic vesicles to advance precision diagnostics and medicine by combining the beneficial properties of naturally occurring extracellular vesicles and synthetic nanoparticles, although no new clinical results are reported.

This source reports on advances in stimulus-responsive nanoparticle-based PROTACs (nano-PROTACs), which aim to overcome existing challenges like poor cell permeability and systemic off-target effects by enabling controlled protein degradation through endogenous or exogenous stimuli, potentially enhancing therapeutic efficacy and reducing toxicity.

This review reports that chitosan-based systems with metal nanoparticles and polyphenols may enhance wound healing by improving the bioavailability and stability of these compounds, suggesting a potential new approach for chronic and diabetic wounds.

This study suggests that combining scalp cooling with resveratrol-loaded nanoparticles effectively protects hair follicles from chemotherapy-induced damage, highlighting a potential method to prevent hair loss during cancer treatment.

This study found that encapsulating tamarillo polyphenols in cubosome nanoparticles protected them during digestion and enhanced the nutritional and antioxidant properties of yoghurt when used as a delivery system.

The researchers suggest that combining microneedle technology with nanocarriers could enhance drug delivery systems for treating central neurological diseases due to nanoparticles' ability to prolong blood circulation time and improve brain targeting.

In this study, HA-P5, a nanoparticle derived from peptide and polysaccharide conjugation, effectively reduced acne lesions and sebum production by inhibiting specific receptors in cells, without triggering unfavorable reactions compared to a commercial inhibitor, highlighting HA-P5's potential as a novel acne treatment.

This study developed a stable, cosmetically appealing formulation for the topical delivery of the peptide FOL-005, enhancing skin permeation and maintaining stability by keeping the peptide solid and in a water-free environment with particle sizes under 10 µm.

This review discusses the potential of Lansium domesticum as a herbal medicine, summarizing its traditional uses, nutritional value, bioactivities, and related nanoparticles and pharmaceutical formulations, but reports no new experimental results.

This study demonstrates that massage significantly enhances the follicular targeting of dutasteride-loaded nanocapsules, increasing drug accumulation in hair follicles by up to 5 times.

This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.

This review provides an overview of composite scaffold materials for skin that mimic natural dermal tissue, and highlights their potential in treating chronic wounds like diabetic foot by promoting cellular growth.

This study formulated a nanogel with Bangkal bark extract that showed moderate antibacterial activity against Propionibacterium acnes, with the F3 formulation (8% extract) achieving the highest inhibition zone of 8 mm, suggesting potential as a natural acne treatment.

The researchers in this experimental study developed a thermodynamic model using the Peng-Robinson equation of state to optimize gas antisolvent system conditions for controlling finasteride particle size, aiming to reduce experimental trials and precisely identify precipitation pressures across different temperatures.

In this study, a pH-responsive microneedle patch was developed, showing potential in rat models for treating spinal cord injuries by reducing inflammation, promoting nerve regeneration, and supporting neurogenesis, which contributed to improved motor and neurological recovery.

This review critically analyzes recent literature on the use of nanotechnology in alopecia treatment, reporting promising results for improving drug delivery and hair growth, though challenges in maintaining physical stability may limit large-scale commercialization.

This study found that adapalene-loaded nanospheres in a hyaluronic acid gel enhanced skin penetration and were nonirritant, making them potentially suitable for treating acne on oily skin.

This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.

The researchers evaluated scientific data on the usage and pharmaceutical applications of ascorbic acid derivatives, such as ascorbyl-6-palmitate and ascorbyl-2-glucoside, highlighting their development into stable delivery platforms to overcome ascorbic acid's instability and formulation challenges.

In this study, researchers optimized fast-dissolving tablets of nifedipine using a systematic approach, resulting in formulations that demonstrated rapid disintegration, enhanced dissolution profiles, and improved solubility, potentially improving oral delivery for patients requiring poorly soluble antihypertensive medication.

This review discusses various therapeutic strategies targeting platelet-derived growth factor signaling in diseases like cancer and atherosclerosis, and evaluates existing treatments without presenting new clinical data.

This study describes Hg(OTf)2 as a new and efficient catalyst for various organic synthesis reactions, including alkyne hydration and C–C bond forming cyclizations.

This review article summarizes recent strategies to enhance the precise control of CRISPR/Cas9 gene editing, addressing tissue-specific challenges and off-target effects by exploring various activation methods like cell-specific promoters and small molecules.

This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.

The microneedle arrays effectively promote wound healing and have potential for clinical use.

This review discusses various applications of CRISPR-based tools in cancer research, emphasizing their potential for investigating microRNA functions and developing microRNA-based therapies, despite challenges like off-target effects and delivery issues in using CRISPR/Cas9.