Design, Optimization, and In Vitro Characterization of Fast-Dissolving Tablets of Nifedipine Using Response Surface Methodology

A user is trying to make a topical finasteride solution by crushing tablets into ethanol and glycerin but struggles with spillage. Suggestions include letting the tablets dissolve in the solution or using a pill crusher for efficiency.

The conversation discusses DIY topical finasteride, with users sharing experiences and advice on dissolving crushed pills in a solvent. Some recommend using raw finasteride powder or buying pre-made solutions for better stability and effectiveness.

OP is trying to dissolve finasteride powder for a topical solution but faces issues with it not dissolving properly in ethanol or water. Users suggest methods like using a magnetic stirrer, shaking the mixture, or filtering out fillers, with some noting that finasteride is soluble in alcohol.

Finasteride pills don't fully dissolve in a DIY topical solution due to fillers, resulting in residue. Users suggest shaking well before application and note that commercial solutions appear clearer.

Crushing finasteride pills into stemoxydine may not be effective without removing the coating first. It's unclear if the pills dissolve completely or settle as sediment.

The user is attempting to create a topical finasteride solution by mixing crushed finasteride pills with minoxidil but is facing solubility issues. They are unsure if the finasteride has dissolved properly and are seeking advice on whether it is safe to use and if there is a solution to the problem.