Progress in the Design of Ascorbic Acid Derivative-Mediated Drug Delivery

The document discusses the increasing popularity of antioxidant-based pharmaceuticals, focusing on ascorbic acid (AA) due to its potent antioxidant properties. Despite its benefits, AA's instability and delivery challenges have led to the development of stable derivatives like ascorbyl-6-palmitate (AP) and ascorbyl-2-glucoside (AA-2G). These derivatives have been extensively studied for their use in drug delivery platforms, particularly nano-sized ones, and their pharmaceutical applications are evaluated, highlighting their potential in enhancing drug delivery systems.