80 citations
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April 2006 in “Clinical Interventions in Aging” This review discusses factors affecting hair aging and the current pharmacological treatments for androgenetic alopecia, mentioning topical minoxidil and oral finasteride, but does not present new clinical findings.
70 citations
,
February 2009 in “Biological Trace Element Research” 36 citations
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May 2025 in “Antioxidants” This study found that lipid peroxidation products play a clear role in the pathogenesis of skin diseases like psoriasis, vitiligo, and alopecia, but their role in diseases like melanoma and atopic dermatitis remains unclear.
29 citations
,
March 2022 in “Biomedicines” This review discusses recent findings on cellular antioxidant responses to oxidative stress and their implications for treating various human diseases but reports no new clinical results.
15 citations
,
January 2017 in “Pigment International” This article reviews the pathogenesis and treatment approaches for premature graying of hair, noting the unsatisfactory options currently available, and reports no new clinical findings.
14 citations
,
September 2023 in “Frontiers in Nutrition” This source observed that while supplementation with pro-, pre-, and synbiotics showed some beneficial effects for PCOS-related outcomes, the evidence quality was deemed low to very low, highlighting the need for further well-designed randomized controlled trials in women with PCOS.
13 citations
,
January 2015 in “International Journal of Trichology” This study found that cadmium levels were significantly higher in women with chronic telogen effluvium compared to healthy controls, suggesting cadmium toxicity might contribute to this hair shedding condition.
8 citations
,
September 2024 in “International Journal of Molecular Sciences” This review discusses how polymers can be customized to develop biomaterials that mimic the extracellular matrix, exploring their potential in biomedical and biotechnological applications by triggering cell functions similar to natural physiological systems.
7 citations
,
August 2025 in “Journal of Nanobiotechnology” This review highlights the potential of microneedles and nanomedicine in advancing tissue regeneration, emphasizing their innovative, localized, and minimally invasive approaches as promising solutions to current challenges in treating chronic wounds and degenerative diseases.
6 citations
,
August 2023 in “Journal of Investigative Dermatology” This study investigated how keratinocytes in the skin respond to different iron levels and found they play a significant role in regulating iron homeostasis by storing iron, affecting epidermal differentiation, and influencing inflammation-related gene expression in mice.
3 citations
,
June 2025 in “Biomedical Reports” This review highlights that nanotechnology shows promise in improving cervical cancer treatment by specifically targeting cancer cells, potentially enhancing treatment efficacy and reducing side effects compared to conventional therapies.
2 citations
,
June 2025 in “International Journal of Molecular Sciences” In this study, Carthamus caeruleus root juice exhibited in vitro anti-inflammatory effects by stabilizing human erythrocyte membranes and inhibiting albumin denaturation, as well as showing potential inhibition of COX-2 through in silico analysis; however, further research is needed to confirm efficacy and mechanisms.
2 citations
,
January 2019 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study found that both a nutritional supplement and a topical hair lotion reduced hair loss and increased the anagen to telogen hair ratio in individuals with androgenetic alopecia.
1 citations
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February 2023 in “International Journal of Molecular Sciences” This study found that exogenous melatonin improved cashmere fiber quality and yield in goats by enhancing antioxidant capacity and reducing pro-aging cytokine expression in secondary hair follicles.
March 2026 in “Pharmaceutics” This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.
July 2025 in “Nano Research” This review highlights the application of microneedle technology as a promising advancement in psoriasis management, focusing on its roles in enhanced transdermal drug delivery and minimally invasive biomarker monitoring, while also discussing current challenges and future research directions.
March 2025 in “Frontiers in Veterinary Science” In this study, altering the photoperiod in goats increased hormone concentrations and improved hair follicle development and skin antioxidant capacity, suggesting that short photoperiods may create favorable conditions for cashmere growth.
October 2023 in “Biomaterials” This review highlights the potential of nanotechnology for hair follicle regeneration, focusing on strategies such as hair cycle modulation, progenitor cell stimulation, and wound-induced hair neogenesis, while also discussing regulatory challenges that may affect the development of these innovative approaches.
The authors describe a case where a 24-year-old woman experienced diffuse hair loss, likely telogen effluvium, after bariatric surgery, suggesting nutritional deficiencies and multifactorial causes may contribute to this condition.
November 2025 in “Stem Cell Research & Therapy” In this study, the authors reported that combining PMSC-secretome and Wnt10b in a GelMA hydrogel scaffold promoted effective hair follicle biofabrication and hair growth in a small in vivo experiment. They emphasized the need for larger studies to confirm these results.
4 citations
,
October 2024 in “International Journal of Molecular Sciences” This study found that chitosan nanoparticle-encapsulated Cordyceps militaris significantly reduced inflammation and oxidative stress in particulate matter-exposed mice, suggesting potential use for managing lung inflammation.
1 citations
,
November 2023 in “Journal of cosmetic dermatology” This study developed a novel antidandruff shampoo with ketoconazole-coated zinc oxide nanoparticles that showed enhanced antifungal activity against Malassezia furfur compared to standard ketoconazole treatments, suggesting it could be a more effective alternative for dandruff management.
130 citations
,
December 2022 in “Antioxidants” This review discusses the antioxidant activity of natural polysaccharides, highlighting their potential applications in areas like drug delivery and tissue engineering, but reports no new experimental findings.
68 citations
,
May 2024 in “International Journal of Molecular Sciences” This review of acne management strategies highlights current treatments, such as topical and systemic therapies, procedural methods, and dietary changes, while also discussing emerging options like biologics and probiotics as potential future treatments, emphasizing personalized care due to acne's complex nature.
68 citations
,
January 2022 in “International Journal of Molecular Sciences” This review summarizes factors involved in polycystic ovary syndrome pathogenesis and management, highlights commonly prescribed and repurposed medications, and calls for well-designed clinical trials to evaluate these treatments further.
45 citations
,
May 2024 in “International Journal of Molecular Sciences” This manuscript reviews the latest understanding of alopecia areata's pathogenesis, highlighting the roles of genetic, immunological, and environmental factors, with a focus on immune responses involving IFN-γ and cytotoxic CD8+ T-cells as key contributors to hair follicle inflammation and function disruption without follicle destruction.
43 citations
,
September 2021 in “Nutrients” This review discusses the vast potential uses of persimmon beyond its dietary benefits, including applications in sustainability and new product development, but reports no new clinical outcomes.
35 citations
,
January 2024 in “BioMolecular Concepts” This review discusses the relationship between oxidative stress and polycystic ovarian syndrome and reports no new clinical results; the authors emphasize the need for further research into therapeutic strategies.
29 citations
,
November 2022 in “Nature Medicine” This study identified thousands of variant-metabolite associations in the human plasma metabolome, offering insights into the genetic bases of metabolism and potential adverse drug effects.
26 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” This review discusses mesenchymal stromal cell-conditioned medium for various skin conditions and found improvements in wound healing, hair restoration, and more, but emphasizes the need for further research to validate these findings.