Biomaterials Mimicking Mechanobiology: A Specific Design for a Specific Biological Application

This review explores how polymers can be used to create biomaterials that mimic the Extracellular Matrix (ECM) to regulate cellular functions through mechanosensing and mechanotransduction pathways. By tailoring the chemical composition, assembly structure, and physical properties of these polymers, biomaterials can be designed to replicate the natural physiological responses of cells. The document discusses various natural and synthetic polymers and their customization for developing biomaterials with specific properties, highlighting their potential applications in biomedical and biotechnological fields.