Revolutionizing Psoriasis Care: Microneedle Innovations in Treatment and Diagnosis

    July 2025 in “ Nano Research ”
    Wanshan Hu, Hongwei Pan, Zhu Jiang, Jiawei Jian, Chunxian Zhou, Mingyu Gong, Ziwei Lai, Chao Lü, Guilan Quan, Chuanbin Wu, Xin Pan, Junhuang Jiang, Tingting Peng
    TLDR Microneedles offer a promising, less invasive way to treat and monitor psoriasis.
    Microneedle (MN) technology is showing significant promise in revolutionizing psoriasis care by improving both treatment and diagnosis. MNs can bypass the skin barrier to deliver drugs directly to psoriatic lesions, enhancing therapeutic outcomes and allowing for the co-delivery of multiple drugs. They also enable minimally invasive biomarker extraction for real-time disease monitoring. Various MN types, such as dissolving and coated MNs, offer distinct advantages, including reduced systemic side effects and enhanced drug efficacy. Recent studies have demonstrated the effectiveness of MNs in delivering drugs like methotrexate and tacrolimus, significantly alleviating psoriasis symptoms in animal models. Despite challenges in manufacturing and large-scale production, MN technology holds potential for personalized medicine, offering innovative strategies for efficient, targeted drug delivery and improved patient outcomes in psoriasis management.
    Discuss this study in the Community →

    Research cited in this study

    8 / 8 results

    Related Community Posts Join

    6 / 1000+ results

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 1 year ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

      community microneedling, do the gains go away?

      in Microneedling  23 upvotes 3 years ago
      Microneedling promotes hair growth by increasing circulation and collagen production, with gains potentially lasting longer than those from minoxidil. Some users report sustained results after stopping microneedling, unlike with minoxidil and finasteride.

      community 2.5 years Minoxidil and HRT, CPA->Lupron +Minox 5%

      in Transgender  611 upvotes 1 year ago
      The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community What an amazing time to be alive

      in Finasteride/Dutasteride  187 upvotes 2 years ago
      The post discusses a user's experience with hair loss treatments, specifically topical finasteride, minoxidil, and micro-needling, and their plan to switch to oral versions and add Dutasteride. The conversation includes various responses, with some users sharing their own experiences and side effects, and others expressing desire for a more permanent hair loss solution.

    Similar Research

    5 / 960 results