Tissue Engineering in Cosmetics and Dermatology: A New Era of Innovation and Application

July 2025 in “ The Open Dermatology Journal ”

Ali Golchin, Maryam Rahnama, Mohammad Saleh Chapani, Forough Shams, Mahmood Rekabgardan, Zahra Poursalehi, Parviz Ranjbarvan

tissue engineering lab-grown skin personalized skin grafts biomaterials scaffold design cellular manipulation skin regeneration wound healing scarring aging

Studysummary This study explores the transformative role of tissue engineering in cosmetics, highlighting innovations like lab-grown skin and personalized grafts that enhance product efficacy, offer ethical alternatives to animal testing, and address aesthetic issues such as scarring and aging.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The document highlights the transformative impact of tissue engineering in cosmetics and dermatology, emphasizing its potential to revolutionize skincare, hair care, and reconstructive procedures. Key innovations include lab-grown skin for testing, personalized skin grafts, and the use of biomaterials like collagen and hyaluronic acid for skin regeneration and anti-aging benefits. Techniques such as 3D bioprinting and bio-inking are advancing the creation of skin models, offering ethical alternatives to animal testing. In hair care, tissue engineering focuses on rejuvenating hair using chitin and chitosan nano-fibrils, while in oral care, it aims at enamel regeneration and oral mucosa reconstruction. The document also discusses the role of tissue engineering in cleft palate/lip reconstruction, lip augmentation, and breast implants, highlighting the use of biocompatible scaffolds and stem cells. Despite the promising advancements, ethical and regulatory challenges remain, necessitating multidisciplinary collaboration for responsible development.

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