Regulation Of Epidermal Ferritin Expression Influences Systemic Iron Homeostasis

    August 2023 in “ Journal of Investigative Dermatology ”
    Shadi Khalil, Kellen Cavagnero, Michael R. Williams … Richard L. Gallo
    Studysummary This study investigated how keratinocytes in the skin respond to different iron levels and found they play a significant role in regulating iron homeostasis by storing iron, affecting epidermal differentiation, and influencing inflammation-related gene expression in mice.
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    Research cited in this study 2

    1. Ferrous Ferric Chloride Stimulates Skin Cell Function and Hair Growth in Mice Biological & pharmaceutical bulletin · 2009
    2. Stratum-Specific Expression of Human Transferrin Receptor Increases Iron in Mouse Epidermis Journal of Investigative Dermatology · 2006