Ferrous Ferric Chloride Stimulates Skin Cell Function and Hair Growth in Mice

In the 2009 study, Ferrous Ferric Chloride (FFC) was shown to stimulate skin cell function and hair growth in mice. The treatment with FFC resulted in increased proliferation and differentiation of epidermal keratinocytes, dermal fibroblasts, and melanocytes, as well as enhanced hair growth and inhibition of alopecia-related hair loss. The study involved applying FFC-containing lotions on the dorsal skin of newborn C57BL/10JHir mice, with a total of 18 or 42 mice used across repeated experiments. The findings suggest that FFC may activate growth factors and hormones involved in skin and hair cell function and could potentially restore gene expression defects related to alopecia. However, the exact number of mice used in the study was not specified in the last part of the summary.