Iron Metabolism of the Skin: Recycling Versus Release

    September 2023 in “ Metabolites ”
    Marta Surbek, Supawadee Sukseree, Leopold Eckhart
    Studysummary This study reviews iron metabolism in the skin, highlighting how differentially expressed genes regulate iron recycling in the epidermis, and discusses changes in iron metabolism related to skin diseases.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 11

    1. Regulation Of Epidermal Ferritin Expression Influences Systemic Iron Homeostasis Journal of Investigative Dermatology · 2023
    2. Autophagy Controls the Protein Composition of Hair Shafts ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2023
    3. Transglutaminase Activity Is Conserved in Stratified Epithelia and Skin Appendages of Mammals and Birds International journal of molecular sciences · 2023
    4. Transcriptome Profiling of Pilosebaceous Units in Male Androgenetic Alopecia Reveals Altered Junctional Networks Journal of Investigative Dermatology · 2021
    5. Biallelic HEPHL1 Variants Impair Ferroxidase Activity and Cause an Abnormal Hair Phenotype PLOS genetics · 2019
    6. Choreographing Immunity in the Skin Epithelial Barrier Immunity · 2019
    7. Human Hair Shaft Proteomic Profiling: Individual Differences, Site Specificity, And Cuticle Analysis PeerJ · 2014
    8. Cell Death by Cornification Biochimica et biophysica acta. Molecular cell research · 2013
    9. Growth Retardation and Hair Loss in Transgenic Mice Overexpressing Human H-Ferritin Gene Transgenic Research · 2012
    10. Scratching the Surface of Skin Development Nature · 2007
    11. Stratum-Specific Expression of Human Transferrin Receptor Increases Iron in Mouse Epidermis Journal of Investigative Dermatology · 2006