research Clinical and Biological Impact of the Exposome on the Skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
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research Biocompatible Nanoparticles and Vesicular Systems in Transdermal Drug Delivery for Various Skin Diseases
Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
research Aging and Anti-Aging in Hair and Hair Loss
Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
research CD98hc (SLC3A2) Regulation of Skin Homeostasis Wanes With Age
CD98hc's role in skin health decreases with age.
research The Interplay Between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation
Finasteride in male rats causes liver and metabolic issues in their offspring.
research In Vivo Immunological Toxicity in Mice of Carbon Nanotubes with Impurities
Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.
research Opposing Impacts on Healthspan and Longevity by Limiting Dietary Selenium in Telomere Dysfunctional Mice
Low selenium levels can extend lifespan but worsen health issues.
research Application of Non-Pharmacologic Therapy in Hair Loss Treatment and Hair Regrowth
Non-drug therapies show promise for hair regrowth but need more research.
research Topical Absorption and Systemic Toxicity
Some chemicals absorbed through the skin can cause serious health problems.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Effects of Parthenolide on Androgenetic Alopecia in Mice and Human Follicle Dermal Papilla Cells
Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.
research Human Hair and the Impact of Cosmetic Procedures: A Review on Cleansing and Shape-Modulating Cosmetics
Future hair cosmetics will be safer and more effective.
research Dermal Adipose Tissue Has High Plasticity And Undergoes Reversible Dedifferentiation In Mice
Dermal adipose tissue in mice can change and revert to help with skin health.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress During Hair Cycling
Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
research MTOR Signaling in Hair Follicle and Hair Diseases: Recent Progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
research N-Terminal Functional Domain of Gasdermin A3 Regulates Mitochondrial Homeostasis via Mitochondrial Targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
research Association of Oxidative Stress in Mild Patchy Alopecia Areata: A Case-Control Study
Oxidative stress is linked to mild patchy alopecia areata.
research Thiolated and PEGylated Silica Nanoparticle Delivery to Hair Follicles
Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
research Toxicity of Repeated Oral Intake of Organic Selenium, Inorganic Selenium, and Selenium Nanoparticles: A Review
Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.
research Ovine Placental Steroid Synthesis and Metabolism in Late Gestation
Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
research Particulate Matter 2.5 Damages Skin Cells by Inducing Oxidative Stress, Subcellular Organelle Dysfunction, and Apoptosis
Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Oncogenic Senescence: A Multi-Functional Perspective
Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
research A Pilot Study of ICG Laser Therapy of Acne Vulgaris: Photodynamic and Photothermolysis Treatment
ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.
research Clinical Patterns of Hair Loss in Men
The document concludes that more research is needed to understand hair loss in men and to find new treatments.
research Oral Manifestations of Hematologic and Nutritional Diseases
Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.
research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production
Hair color is determined by melanin produced and transferred in hair follicles.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Immunological And Some Biological Biomarkers Investigation In Patients With Systemic Lupus Erythematosus
No single biomarker is reliable enough for diagnosing and assessing SLE.