1 citations
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February 2023 in “Applied sciences” This study found that methylcellulose-based hydrogels can effectively deliver growth hormone through the skin, with albumin increasing the hormone's permeation to 93% in simulated in vivo conditions.
138 citations
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August 2020 in “Frontiers in Endocrinology” This review discusses expert consensus on PCOS, emphasizing its impacts and supporting evidence-based treatments, while recommending further research into nutraceutical benefits for managing the condition; it reports no new clinical results.
4 citations
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January 2025 in “International Journal of Yoga” This study found that regular yoga practice could benefit women with PCOS by improving hormonal balance, mitochondrial health, oxidative stress, and inflammation, while also reducing depression symptoms, suggesting yoga as a supportive therapy for managing PCOS.
April 2026 in “Biomolecules” This review highlights recent advancements in molecular understanding and treatment approaches for PCOS, including innovative drug delivery systems and AI-driven precision medicine, but provides no new clinical results.
18 citations
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October 2022 in “Biomedicines” This review discusses the role of anti-Müllerian hormone in polycystic ovary syndrome and its male equivalent, but reports no new clinical findings; it suggests further investigation is needed into male relatives' reproductive function.
4 citations
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January 2024 in “Therapeutic Advances in Reproductive Health” This study found significant correlations between old and new ultrasound devices for measuring NF and ovarian volume, being the first on the African continent to reassess ultrasound criteria for PCOS.
11 citations
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January 2020 in “World Journal of Traditional Chinese Medicine” This study used a glucocorticoid-injection model to mimic kidney-yang deficiency syndrome and reported symptoms related to hormonal imbalances in the hypothalamic-pituitary-target gland axes.
4 citations
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September 2025 in “Biomolecules” This narrative review discusses the mixed and evolving evidence regarding glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and their influence on erectile dysfunction in men with type 2 diabetes and obesity, highlighting potential benefits and concerns yet to be clarified.
August 2025 in “Obstetrics and gynecology.” This article reviews the management of polycystic ovarian syndrome, highlighting lifestyle modification and individualized pharmacological treatment strategies, and reports no new clinical results.
March 2025 in “Annals of Medicine and Surgery” This review discusses the pathophysiology, diagnosis, management, and psychosocial impact of skin manifestations in PCOS and emphasizes the need for holistic, personalized care without reporting new results.
February 2025 in “Clinical Chemistry” This case study reported a 34-year-old woman presenting with secondary amenorrhea, hirsutism, and obesity showed elevated testosterone and anti-Müllerian hormone levels, leading to the exclusion of nonclassical congenital adrenal hyperplasia as a diagnosis.
January 2017 in “Open Journal of Endocrine and Metabolic Diseases” This case report identifies an adolescent with symptoms indicative of Dunnigan-type partial lipodystrophy, emphasizing the need for early diagnosis to manage associated metabolic complications and improve self-esteem.
63 citations
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August 2022 in “Diagnostics” This review discusses hirsutism in women with PCOS who present with normal androgen levels and highlights diagnostic challenges, reporting no new clinical findings.
55 citations
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August 2003 in “Ultrasound in Obstetrics and Gynecology” This study suggests that ultrasound and color Doppler analyses may enhance the differential diagnosis of GnRH-dependent precocious puberty in girls with premature breast development or pubic hair growth.
17 citations
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August 2003 in “Ultrasound in Obstetrics and Gynecology” This review discusses the complexities of diagnosing polycystic ovary syndrome and reports no new results; the authors suggest a thorough and careful diagnostic approach to avoid misdiagnosis and unnecessary tests.
4 citations
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March 2024 in “Applied Physiology Nutrition and Metabolism” In this review, researchers highlight that interval training may offer superior cardiometabolic benefits for reproductive-aged females at different life stages compared to continuous exercise, but further research is needed to validate physical activity recommendations for this group.
2 citations
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September 2021 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan” In this study, researchers observed that while there were no significant microvascular abnormalities in the macula of PCOS patients, the parafoveal thickness was significantly increased in most quadrants.
May 2025 in “Veterinary Medicine and Science” In this study, oral melatonin given to male Pomeranian dogs with Alopecia X improved semen quality and testicular blood flow in a dose-dependent manner, but altered hormonal balance, indicating complex effects that require further investigation for long-term implications.
400 citations
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January 2014 in “British Journal of Sports Medicine” This consensus statement discusses guidelines for screening, diagnosing, and treating the Female Athlete Triad, and introduces a risk stratification system to assist healthcare providers with sports participation decisions.
175 citations
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January 2020 in “European Journal of Endocrinology” These guidelines recommend testing thyroid function in patients with obesity due to common hypothyroidism, and highlight that weight loss is crucial for addressing hormonal imbalances, with only modest weight loss benefits from treating endocrine disorders.
47 citations
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September 2022 in “European Heart Journal” This consensus document reviews current knowledge on sex differences in essential hypertension and identifies areas needing further research to improve sex-specific prevention and management strategies.
44 citations
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September 2020 in “International Journal of Molecular Sciences” This review discusses the disruption of hormonal and metabolic rhythms in polycystic ovary syndrome and explores potential drug targets to address its molecular causes, without providing new clinical results.
27 citations
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May 2002 in “The Journal of Clinical Endocrinology & Metabolism” This study found that brothers of women with PCOS exhibit elevated DHEAS levels, indicating a potential familial genetic trait, but did not show increased rates of premature balding.
19 citations
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March 2022 in “International Journal of Environmental Research and Public Health” This review covers the neuroendocrine aspects of polycystic ovary syndrome, focusing on hormones and neurotransmitters like GnRH and kisspeptin, but does not report new clinical findings.
12 citations
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February 2025 in “Women s Health” This paper reports that while metformin may improve fertility outcomes and reduce miscarriage rates in women with PCOS, its efficacy can differ depending on the specific treatment combination used.
12 citations
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January 2022 in “International Journal of Clinical Practice” This study found that women with PCOS, especially those who are obese, showed higher oxidative stress and decreased antioxidant levels, correlating with metabolic syndrome and cardiovascular disease risk factors.
10 citations
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November 2024 in “Diagnostics” This review discusses the role of elevated androgens in the skin-related symptoms of polycystic ovary syndrome, such as acne and hirsutism, and provides insights into the mechanisms behind these manifestations to inform effective treatment strategies.
1 citations
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December 2024 in “Journal of Clinical Medicine” This study found that in overweight or obese women with PCOS and insulin resistance, those with lower baseline prolactin levels exhibited a greater decrease in insulin resistance after 6-8 months of metformin treatment, compared to those with higher prolactin levels.
May 2026 in “Endocrine Connections” This review posits that alopecia in PCOS results from the interaction between local follicular signaling failures, insulin resistance, inflammation, and genetic predispositions, rather than solely from androgen excess, and recommends a systems-level framework for its management.
January 2026 in “International Journal of Molecular Sciences” This narrative review highlights that declining testosterone levels are a complex public health issue potentially influenced by modifiable lifestyle factors and environmental stressors, suggesting integrated strategies may be needed to address the trend's impacts on health.