Anti-Müllerian Hormone and Polycystic Ovary Syndrome in Women and Its Male Equivalent

    October 2022 in “ Biomedicines
    Nathalie di Clemente, Chrystèle Racine, Rodolfo A. Rey
    TLDR High AMH levels are linked to PCOS in women and may have a male equivalent with similar traits.
    This review examined the role of Anti-Müllerian Hormone (AMH) in the development of Polycystic Ovary Syndrome (PCOS) in women and its potential male equivalent. In women, elevated AMH levels were linked to increased follicle numbers, androgen levels, and symptoms such as follicular arrest and anovulation, contributing to PCOS. The study also noted that male relatives of women with PCOS often showed metabolic issues and early-onset androgenic alopecia, suggesting a male equivalent of PCOS. The review highlighted the genetic transmission of PCOS traits and the complex interactions of AMH in reproductive and endocrine processes, emphasizing the need for further research on AMH's role in both female and male reproductive health.
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