Pelvic Ultrasound and Color Doppler Findings in Different Isosexual Precocities

The study from 2003 evaluated the use of pelvic ultrasound and color Doppler analyses in diagnosing different forms of isosexual precocity in 69 girls under 8 years old. It found that uterine artery Doppler analysis was effective in diagnosing GnRH-dependent precocious puberty, offering a non-invasive method to assess the hypothalamic–pituitary–ovarian axis's activity. The study highlighted that increased uterine volume and midline endometrial echo had high specificity and sensitivity, correlating well with the GnRH-stimulation test. Doppler analysis of uterine arteries was more effective than sonography alone in distinguishing true precocious puberty, emphasizing the importance of accurate diagnosis to avoid unnecessary treatment.