Secondary Amenorrhea and Clinical Hyperandrogenism in a 34-Year-Old Female: Polycystic Ovary Syndrome or Not?

    February 2025 in “ Clinical Chemistry ”
    Sameen Hassan, Beth M Lalande, Robert D Nerenz
    Studysummary This case study reported a 34-year-old woman presenting with secondary amenorrhea, hirsutism, and obesity showed elevated testosterone and anti-Müllerian hormone levels, leading to the exclusion of nonclassical congenital adrenal hyperplasia as a diagnosis.
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    Research cited in this study 3

    1. Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome European journal of endocrinology · 2023
    2. Epidemiology, Diagnosis, and Management of Hirsutism: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome Society Human reproduction update · 2011
    3. Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS) Human Reproduction · 2003

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    2. Correlation of Clinical and Biochemical Hyperandrogenism in Thai Women with Polycystic Ovary Syndrome Journal of Obstetrics and Gynaecology Research · 2016
    3. Hyperandrogenism in Women: Polycystic Ovary Syndrome Hanyang Medical Reviews · 2012
    4. Polycystic Ovary Syndrome and Acne Skin therapy letter · 2011
    5. Hirsutism Scoring in Polycystic Ovary Syndrome: Concordance Between Clinicians' and Patients' Self-Scoring Fertility and Sterility · 2010
    6. Diagnosis of Hyperandrogenism: Clinical Criteria Best Practice & Research Clinical Endocrinology & Metabolism · 2006
    7. Spironolactone Therapeutic Effect in the Hyperandrogenism Syndrome Problemy e̊ndokrinologii · 1993