5 citations
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November 2001 in “PubMed” This case report describes an 80-year-old woman with severe androgenic alopecia linked to Leydig cell hyperplasia in an ovarian cyst, highlighting the need to investigate androgen-secreting tumors in similar cases.
5 citations
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November 2018 in “Journal of Obstetrics and Gynaecology” This case series highlights that diagnosing ovarian Leydig cell tumors can be challenging, and expert sonography is crucial for accurate identification, as imaging modalities like CT, MRI, and PET-CT may fail to detect them.
4 citations
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January 2007 in “Gynecological endocrinology” This case study suggests that low leptin levels in obese hyperandrogenic postmenopausal women might indicate the presence of androgen-secreting tumors.
1 citations
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March 2012 in “Journal of pediatric & adolescent gynecology” This case report suggests that PCOS can present with virilization and rapidly increasing testosterone levels, and highlights oral contraceptives' effectiveness in managing hyperandrogenism in such cases.
July 2026 in “Frontiers in Endocrinology” This case report describes a 19-month-old girl with androgen-dominant virilization caused by an adrenal tumor, highlighting the importance of adrenal assessment in young girls with such symptoms and recommending long-term monitoring even after initial biochemical remission.