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Glossary Leydig Cell Tumor

rare testicular tumor from testosterone-producing Leydig cells

A Leydig Cell Tumor is a rare type of tumor that originates from the Leydig cells, which are found in the testes and are responsible for producing testosterone. These tumors can occur in both children and adults and may cause symptoms such as testicular swelling, pain, or hormonal imbalances. While most Leydig Cell Tumors are benign, a small percentage can be malignant and may require surgical removal and further treatment.

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research Ovarian Leydig cell tumor in a post-menopausal patient with severe hyperandrogenism

22 citations , February 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia”

An 81-year-old woman's severe male hormone symptoms were caused by an ovarian tumor, which was treated with surgery.

research An ovarian Leydig cell tumor of ultrasound negative in a postmenopausal woman with hirsutism and hyperandrogenism

12 citations , March 2018 in “Medicine”

This case report describes a 60-year-old woman with an ovarian Leydig cell tumor leading to elevated testosterone levels and hirsutism, highlighting the need to consider androgen-secreting tumors in similar postmenopausal cases.

research Diagnostic pitfalls in ovarian androgen-secreting (Leydig cell) tumours: case series

5 citations , November 2018 in “Journal of Obstetrics and Gynaecology”

This case series highlights that diagnosing ovarian Leydig cell tumors can be challenging, and expert sonography is crucial for accurate identification, as imaging modalities like CT, MRI, and PET-CT may fail to detect them.

research Menopausal Androgen Excess - Associated Cardio-Metabolic Risk: Clues for Ovarian Leydig Cell Tumour (Case Report and Mini-Review of Literature)

5 citations , January 2017 in “Acta Endocrinologica”

This case report discusses a postmenopausal woman whose hyperandrogenism and metabolic symptoms improved significantly after the surgical removal of an ovarian Leydig cell tumor, confirmed post-operatively.

research “Occult” ovarian Leydig cell tumor: when laboratory tells more than imaging

5 citations , October 2013 in “Endocrine”

This case report describes three instances where occult ovarian Leydig cell tumors were suspected based on severe hyperandrogenism symptoms, despite negative imaging findings, highlighting that elevated testosterone levels are a crucial diagnostic marker.

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