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GlossaryLeydig Cell Tumor

rare testicular tumor from testosterone-producing Leydig cells

A Leydig Cell Tumor is a rare type of tumor that originates from the Leydig cells, which are found in the testes and are responsible for producing testosterone. These tumors can occur in both children and adults and may cause symptoms such as testicular swelling, pain, or hormonal imbalances. While most Leydig Cell Tumors are benign, a small percentage can be malignant and may require surgical removal and further treatment.

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research Ovarian Leydig Cell Tumor in a Post-Menopausal Patient with Severe Hyperandrogenism

22 citations, February 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia”

An 81-year-old woman's severe male hormone symptoms were caused by an ovarian tumor, which was treated with surgery.

research An Ovarian Leydig Cell Tumor Undetected by Ultrasound in a Postmenopausal Woman with Hirsutism and Hyperandrogenism

12 citations, March 2018 in “Medicine”

A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.

research Occult Ovarian Leydig Cell Tumor: When Laboratory Tells More Than Imaging

5 citations, October 2013 in “Endocrine”

Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.

research Ovarian Leydig Cell Tumor and Postmenopausal Hirsutism with Signs of Virilization

4 citations, March 2021 in “Case Reports”

A woman's excessive hair growth and masculine features were due to a rare benign ovarian tumor and endometrial cancer, which improved after surgery.

research Diagnosis of an Indistinct Leydig Cell Tumor by Positron Emission Tomography-Computed Tomography

4 citations, January 2019 in “Obstetrics & gynecology science”

A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.

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community Mechanism of action of alfatradiol (17 alpha estradiol)

in Research/Science 6 upvotes 6 months ago

The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

community FtM: "Aggressive Regemin - Recovery From Norwood-6.5" Minoxodil/Estradiol valerate/Spironolactone. (What will happen in the worst case if CIS male go this way for a year?)

in Progress Pictures 55 upvotes 3 years ago

User "Ant1pal" shares progress pictures of hair regrowth using Minoxidil, Estradiol valerate, and Spironolactone. Users discuss potential side effects and the possibility of localizing estrogen to hair follicles for better treatment.

community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

in Research/Science 37 upvotes 2 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.