The Impact of Glucagon-Like Peptide-1 Receptor Agonists on Erectile Function: Friend or Foe?

    September 2025 in “ Biomolecules ”
    Dimitris Kounatidis, Natalia G. Vallianou, Eleni Rebelos, Kalliopi Vallianou, E. Diakoumopoulou, Konstantinos Makrilakis, Nikolaοs Tentolouris
    TLDR The effect of GLP-1 RAs on erectile function is unclear and needs more research.
    This narrative review explores the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on erectile function, particularly in individuals with type 2 diabetes (T2D). Erectile dysfunction (ED) is a common complication of diabetes, influenced by factors such as age, disease duration, and glycemic control. GLP-1 RAs, known for their glucose-lowering and cardiovascular benefits, are hypothesized to improve erectile function. However, some preliminary reports suggest a potential link between GLP-1 RA use and ED. The review synthesizes current evidence, highlighting the need for further research to clarify the relationship between GLP-1 RAs and erectile function.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results