The Impact of GLP-1 Receptor Agonists on Hair: Beneficial Effects or Adverse Outcomes?

    April 2026 in “ American Journal of Clinical Dermatology ”
    S. Morteza Seyed Jafari, Gemma Caro, Shari R. Lipner, Matilde Iorizzo
    Studysummary GLP-1 receptor agonists may help or harm hair health, needing more research.
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    Research cited in this study 15

    1. Increased Risk of Telogen Effluvium with Tirzepatide Compared to Other Weight-Loss Medications: A Retrospective Cohort TriNetX Database Study Journal of the American Academy of Dermatology · 2025
    2. Association Between Androgenetic Alopecia and Glucagon-Like Peptide-1 Receptor Treatment in Type 2 Diabetes Mellitus Patients: A Retrospective Cohort Study International Journal of Dermatology · 2025
    3. Alopecia and Semaglutide: Connecting the Dots for Patient Safety Journal of Cosmetic Dermatology · 2025
    4. Dermatologic Implications of GLP-1 Receptor Agonist Medications: A Comprehensive Review Skin Appendage Disorders · 2025
    5. Exploring the Hair Loss Risk in Glucagon-Like Peptide-1 Agonists: Emerging Concerns and Clinical Implications Journal of the European Academy of Dermatology and Venereology · 2025
    6. Glucagon-Like Peptide-1 Receptor Agonist Medications and Hair Loss: A Retrospective Cohort Study Journal of the American Academy of Dermatology · 2025
    7. Risk of Suicide, Hair Loss, and Aspiration with GLP1-Receptor Agonists and Other Diabetic Agents: A Real-World Pharmacovigilance Study Cardiovascular Drugs and Therapy · 2024
    8. Treatment of Insulin Resistance With Tirzepatide Leading to Improvement of Hair Loss JAAD Case Reports · 2024
    9. GLP-1 Agonists and Hair Loss: A Call for Further Investigation International Journal of Dermatology · 2024
    10. Association of Obesity and Bariatric Surgery on Hair Health Medicina-lithuania · 2024
    11. The AR/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia International Journal of Biological Sciences · 2023
    12. Telogen Effluvium: A Comprehensive Review Clinical, Cosmetic and Investigational Dermatology · 2019
    13. Insulin-Like Growth Factor-1: Roles in Androgenetic Alopecia Experimental Dermatology · 2014
    14. Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study Indian Dermatology Online Journal · 2014
    15. Glucagon-Like Peptide-1 Receptor and Proglucagon Expression in Mouse Skin Regulatory Peptides · 2006