A Narrative Review on Cutaneous Manifestations in Polycystic Ovary Syndrome: Pathophysiology, Diagnosis, Management, and Psychosocial Impact

March 2025 in “ Annals of Medicine and Surgery ”

Muhammad Farhan, Ariana Seyfi, Abdulla Alnuaimi, Maya Alamour, Sarah Alwarafi, Haya Elastal, Muhammad Hashir Nazir, Balakrishnan Kamaraj, Hrithik Dakssesh Putta Nagarajan, Deborah Delianne, Shyamala Ganesan, Tirath Patel

polycystic ovary syndrome PCOS acne hirsutism androgenic alopecia hyperandrogenism insulin resistance hormonal interventions dermatological interventions lifestyle interventions

Studysummary This review discusses the pathophysiology, diagnosis, management, and psychosocial impact of skin manifestations in PCOS and emphasizes the need for holistic, personalized care without reporting new results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This narrative review examines the skin-related symptoms of polycystic ovary syndrome (PCOS), such as acne, hirsutism, and androgenic alopecia, which are linked to hormonal and metabolic imbalances. These conditions significantly affect the quality of life and mental health of individuals with PCOS. The review discusses the pathophysiology involving hyperandrogenism and insulin resistance and suggests a combination of hormonal, dermatological, and lifestyle interventions for management. It highlights the importance of personalized care and the integration of psychological support to address the psychosocial impact. Future research is needed to develop personalized therapies to improve outcomes for PCOS patients.

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