Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome

    June 2018 in “ Journal of Womens Health ”
    Uche Ezeh, Andy Huang, Melanie Landay, Ricardo Azziz
    Studysummary This study found that in women with PCOS, suppressive therapy using spironolactone plus oral contraceptives improved hirsutism more effectively than either treatment alone, with initial scores predicting success.
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    Research cited in this study 20

    1. Evidence-Based Approach to Cutaneous Hyperandrogenism in Women Journal of The American Academy of Dermatology · 2015
    2. Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline The Journal of Clinical Endocrinology and Metabolism · 2013
    3. Female Pattern Alopecia: Current Perspectives International Journal of Women's Health · 2013
    4. Changes in the PCOS Phenotype with Age Steroids · 2013
    5. Consensus on Women's Health Aspects of Polycystic Ovary Syndrome: The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group Fertility and sterility · 2011
    6. Epidemiology, Diagnosis, and Management of Hirsutism: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome Society Human reproduction update · 2011
    7. The Hirsute Woman: Challenges in Evaluation and Management Endocrine Practice · 2011
    8. Spironolactone Versus Placebo or in Combination with Steroids for Hirsutism and/or Acne Cochrane library · 2009
    9. The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report Fertility and Sterility · 2008
    10. Antiandrogens for the Treatment of Hirsutism: A Systematic Review and Meta-Analyses of Randomized Controlled Trials ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2008
    11. A Systematic Review of Commonly Used Medical Treatments for Hirsutism in Women Clinical endocrinology · 2007
    12. Hirsutism and the Variable Response of the Pilosebaceous Unit to Androgens Journal of Investigative Dermatology Symposium Proceedings · 2005
    13. Androgen Excess in Women: Experience with Over 1000 Consecutive Patients The Journal of Clinical Endocrinology and Metabolism · 2004
    14. Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2001
    15. Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2000
    16. Prevalence of Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study The Journal of Clinical Endocrinology and Metabolism · 1998
    17. Prevalence of Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study The Journal of Clinical Endocrinology and Metabolism · 1998
    18. Electrolysis: Observations from 13 Years and 140,000 Hours of Experience Journal of the American Academy of Dermatology · 1995
    19. The Treatment of Hyperandrogenism with Oral Contraceptives Seminars in reproductive medicine · 1989
    20. The Effects of Two Doses of Spironolactone on Serum Androgens and Anagen Hair in Hirsute Women Fertility and sterility · 1985

    Related research 4

    1. High-Dose Spironolactone for Acne in Patients with Polycystic Ovarian Syndrome: A Single-Institution Retrospective Study Journal of The American Academy of Dermatology · 2019
    2. Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome Journal of Womens Health · 2018
    3. Prevalence of Dermatologic Manifestations and Metabolic Biomarkers in Women with Polycystic Ovary Syndrome in North China Journal of Cosmetic Dermatology · 2017
    4. Hirsutism and Acne in Polycystic Ovary Syndrome Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology · 2004