34 citations
,
January 2022 in “Human Reproduction Open” This study found no clinically significant effects of intraovarian injection of platelet-rich plasma on ovarian function over one year in patients with extremely low functional ovarian reserve.
1 citations
,
January 2018 in “Revue Médicale de Bruxelles” This review analyzes existing clinical results on the use of platelet-rich plasma injections for treating androgenetic alopecia but reports no new findings; the authors emphasize the need for further controlled studies.
24 citations
,
January 2018 in “Journal of Visualized Experiments” In this study, 23 patients with androgenetic alopecia were treated with non-activated autologous platelet-rich plasma (A-PRP) administered through interfollicular injections, but the abstract provides no results of the treatment's effectiveness.
July 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” AA-PRP injections significantly promote hair growth but need better study design for clear efficacy.
This study found that intrathyroidal injection of autologous platelet-rich plasma improved thyroid function and symptoms in hypothyroidism patients, without adverse events over one year.
January 2018 in “Journal of Visualized Experiments” This study found that injections of autologous platelet-rich plasma in patients with pattern hair loss were compared to placebo, but the abstract does not report specific clinical results.
183 citations
,
January 2014 in “BioMed Research International” This study reported that AA-PRP injections significantly increased hair count and density in individuals with pattern hair loss compared to baseline, demonstrating their potential for enhancing hair growth.
2 citations
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June 2024 in “Regenerative Therapy” In this study, ozone treatment was shown to increase the concentration of growth factors like EGF and TGF-β in PRP in vitro, suggesting that oxygen-rich PRP injections may provide an effective method for facial rejuvenation.
1 citations
,
January 2023 in “The Egyptian Journal of Hospital Medicine” This study found that combining platelet-rich plasma with microneedling and subcision was effective in treating atrophic acne scars in over 80% of patients with minimal adverse effects.
October 2025 in “Clinical Case Reports” This case report challenges the traditional view by documenting reversible vision loss following scalp injections of platelet-rich plasma, attributed to an inflammatory or microvascular event, treatable with corticosteroids.
September 2025 in “Journal of Cosmetic Dermatology” This study found that both PRP injections and microneedling treatments significantly improved hair count and thickness in patients with androgenetic alopecia, without significant differences between the two methods. Microneedling also enhanced patient satisfaction and treatment tolerance.
March 2025 in “Authorea (Authorea)” This review discusses the use of platelet-rich plasma (PRP) in regenerative plastic surgery and dermatology for hair regrowth and skin revitalization, noting some potential side effects without reporting new clinical results.
1 citations
,
October 2021 in “QJM: An International Journal of Medicine” This study found that platelet-rich plasma prepared using a double-spin method may be more effective for treating female pattern hair loss than single-spin PRP, although VEGF concentration was unaffected by either preparation method.
6 citations
,
August 2024 in “The Laryngoscope” In this study, serial platelet-rich plasma injections improved voice quality and mucosal wave ratings in patients with vocal fold scar, with patient-reported outcomes showing a consistent positive trend.
March 2026 in “Journal of Ovarian Research” This review explores the potential of platelet-rich plasma therapy for early ovarian reserve decline and premature ovarian insufficiency, indicating some ovarian function improvements in initial studies but highlighting the need for further research.
2 citations
,
July 2024 in “Cureus” This review discusses the potential benefits of using autologous endometrial cells and PRP via hysteroscopic injections to improve pregnancy outcomes in ART, particularly in individuals with refractory thin endometrium, but reports no new clinical results.
164 citations
,
January 2014 in “Journal of Cutaneous and Aesthetic Surgery” This study found that PRP injections may improve hair density and reduce hair loss in patients with androgenetic alopecia without significant side effects, but further research is needed to confirm efficacy.
88 citations
,
December 2012 in “Journal of The European Academy of Dermatology and Venereology” This study found that interfollicular injection of autologous CD34+ cell-containing PRP preparation improved hair count and thickness in patients with pattern hair loss, with better results than placental extract treatment.
52 citations
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May 2017 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections significantly improved hair density, thickness, and patient satisfaction in women with female pattern hair loss compared to a placebo.
31 citations
,
March 2020 in “International Journal of Regenerative Medicine” This study found that intraovarian PRP treatment in women with low ovarian reserve was associated with significant increases in serum AMH levels in some patients, typically within four weeks.
30 citations
,
August 2015 in “JAAD case reports” This case report describes a patient with corticosteroid-resistant ophiasis alopecia areata who experienced prompt hair regrowth after receiving platelet-rich plasma injections.
12 citations
,
March 2023 in “The FASEB Journal” This study found that platelet-rich plasma treatment significantly improved erectile function and restored neural structures in aged rats with erectile dysfunction, suggesting potential benefits for geriatric patients.
8 citations
,
January 2020 in “Indian Dermatology Online Journal” In this study, PRP injections showed comparable effectiveness to triamcinolone for alopecia areata, with a significant decrease in SALT score at one interval, and 12.5% of patients in the PRP group experienced excellent hair regrowth compared to none in the triamcinolone group.
7 citations
,
June 2024 in “Skin Research and Technology” Combining treatments significantly reduces dark circles and wrinkles better than nanofat alone.
5 citations
,
January 2020 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study found that PRP was effective for treating alopecia areata with similar improvement across groups, while topical delivery via fractional CO2 laser or microneedling reduced injection pain.
5 citations
,
March 2018 in “Clinics in Dermatology” This study found that combined platelet-rich plasma injections and suture embedding significantly improved scalp thickness, blood flow, and hair diameter in patients with androgenetic alopecia.
4 citations
,
October 2019 in “Skin appendage disorders” This study found that autologous activated PRP injections significantly increased hair density in patients with androgenetic alopecia, with patients reporting high satisfaction and few side effects.
3 citations
,
November 2016 in “Journal of Pakistan Association of Dermatology” This study found that autologous platelet rich plasma (PRP) may be a safe and effective treatment for limited alopecia areata, with varying levels of hair regrowth observed among patients.
2 citations
,
November 2017 in “Journal of Cosmetic Dermatology” In this study, subcutaneous platelet-rich plasma injections improved hair density and histological markers of hair growth in hairless rats without causing local toxicity.
This chapter reviews the combined use of platelet-rich plasma and microneedling for cosmetic enhancement but reports no clinical results; the authors highlight existing uses and suggest potential synergistic benefits in dermatology.