Development of Hyperalgesia in Patients with Androgenetic Alopecia Treated with Autologous PRP
April 2018
in “
Selçuk Üniversitesi Tıp Fakültesi dergisi
”
New to Platelet-Rich Plasma? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that repeated PRP injections in patients with androgenetic alopecia may lead to hyperalgesia, where pain is felt with less stimulus after each treatment. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigated the development of hyperalgesia in patients with androgenetic alopecia treated with autologous platelet-rich plasma (PRP). Ten male patients aged 25-35 received PRP injections in the scalp over a year, experiencing increased pain sensitivity after each application, with the highest hyperalgesia observed in the first year post-treatment (p < 0.05). Hair density increased by 6.4%, 9.4%, 21%, and 27.6% at 1, 2, 6, and 12 months, respectively. The study concluded that repeated PRP injections could cause hyperalgesia, potentially due to growth factors in PRP, and recommended further research to understand this phenomenon.
