Use of Activated PRP on Alopecia: Systematic Review and Meta-Analyses

May 2023 in “ Plastic and reconstructive surgery. Global open ”

Suat Morkuzu, Alexandra McLennan, Muholan Kanapathy, Afshin Mosahebi

activated platelet-rich plasma A-PRP alopecia hair density hair regrowth folliculogenesis hair loss hair cycle terminal hairs PRP

TLDR Activated PRP injections are effective in treating hair loss and improving hair density.

This systematic review and meta-analysis evaluated the clinical effectiveness and safety of autologous activated platelet-rich plasma (A-PRP) injections for treating alopecia. A total of 29 human clinical studies involving 864 patients were analyzed. The majority of studies (27 out of 29) reported positive outcomes, showing that A-PRP significantly improves hair density, promotes hair regrowth, folliculogenesis, reduces hair loss, and initiates the hair cycle. The pooled analysis demonstrated a significant increase in the number of hairs per cm² and terminal hairs per cm² in treated patients compared to controls. This review supports the use of A-PRP as an effective treatment for alopecia.

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