The Effect of Human Lyophilized Growth Factors Versus Platelet-Rich Plasma Injection on Hair Transplantation Outcome in the Crown Area of the Scalp in Men with Androgenetic Alopecia

May 2024 in “ Archives of dermatological research ”

Ahmed R. Elshahid, Amr Mohamed Mostafa, Ahmed Waheed Kheder Fnoon, Mohamed A. Abdelshakour

human lyophilized growth factors platelet-rich plasma hair transplantation crown area androgenetic alopecia hair density hair thickness LGFs PRP

TLDR LGFs slightly improve hair transplant results more than PRP.

The study compared the effects of human lyophilized growth factors (LGFs) and platelet-rich plasma (PRP) injections on hair transplantation outcomes in the crown area of men with androgenetic alopecia. The authors found that both treatments improved hair density and thickness, but LGFs showed a slightly higher efficacy compared to PRP. The study did not generate or analyze any datasets, and all participants provided informed consent. The research was conducted without any funding or conflicts of interest.

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The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

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