21 citations
,
October 2023 in “The Journal of Physical Chemistry C” This study used theoretical calculations to show that phosphates strongly bind to cerium dioxide surfaces in various stable configurations, with spectral signatures identifiable in the infrared and Raman spectra, informing future experimental efforts in controlling the enzymatic activity of ceria nanoparticles.
19 citations
,
January 2023 in “Frontiers in Bioengineering and Biotechnology” This review discusses the therapeutic potential of mesenchymal stem cell-derived small extracellular vesicles for chronic wound treatment and reports no new clinical results, emphasizing the need for further research on their large-scale production and engineering.
18 citations
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May 2022 in “Stem Cell Research & Therapy” This study found that irradiating human adipose-derived stem cells with green OLEDs enhanced their wound healing capability and increased cell proliferation, migration, and adhesion in preclinical models.
17 citations
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November 2015 in “Oxidative Medicine and Cellular Longevity” This study suggests that FGF-9 treatment may improve cardiac function by reducing vascular apoptosis and enhancing angiogenesis in infarcted hearts of both nondiabetic and diabetic mice.
15 citations
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November 2023 in “Immunity & ageing” This review highlights the role of the receptor TLR4 in cellular aging and age-related diseases, suggesting it as a potential therapeutic target due to its contribution to persistent inflammation and symptom regulation in these conditions.
13 citations
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September 2014 in “BMC Complementary and Alternative Medicine” Tanshinone IIA helps protect skin tissue from low oxygen damage by boosting certain cell markers.
12 citations
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May 2024 in “International Journal of Nanomedicine” This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.
12 citations
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October 2023 in “Journal of Mind and Medical Sciences” This source presents a comprehensive review of the literature on diabetes, highlighting the complex factors involved in its development and the importance of prevention, early diagnosis, and a multi-faceted treatment approach for effective management.
12 citations
,
April 2023 in “Frontiers in Materials” This review discusses the biofunctionalization of hydrogel scaffolds for vascular tissue regeneration and reports promising results from in vivo studies, such as improved angiogenesis and healing in pressure ulcers when using specific peptides.
12 citations
,
August 2015 in “Plastic Surgery” This study found that botulinum toxin type A significantly reduced skin flap necrosis in rats exposed to cigarette smoke, suggesting it may help improve flap viability in smokers.
11 citations
,
February 2021 in “Frontiers in Bioengineering and Biotechnology” This study suggests that short-term treatments with specific small molecules may enhance the differentiation potential and stem cell properties of human amniotic fluid stem cells.
10 citations
,
February 2021 in “PLoS biology” This study found that corin, a protease, plays a crucial role in eccrine sweat glands by promoting sweat and salt excretion, which helps regulate electrolyte balance.
10 citations
,
January 2013 in “Regenerative Medicine Research” This article discusses the potential for rejuvenating self-repair mechanisms to enhance regenerative medicine, but reports no new empirical findings.
9 citations
,
August 2025 in “Current Issues in Molecular Biology” This review discusses the role of extracellular vesicles in bone regeneration and their potential as therapeutics, highlighting challenges like standardization and safety for clinical application, but it reports no new clinical results.
9 citations
,
February 2025 in “Journal of Nanobiotechnology” In this study, researchers found that using bioinspired nanovesicles derived from inflammation memory-activated epidermal stem cells effectively promoted healing in diabetic wounds by reprogramming neutrophils to an anti-inflammatory phenotype in both laboratory and animal models.
9 citations
,
January 2021 in “Acta Cirúrgica Brasileira” This study found that DPG promoted wound healing in rat skin, with increased collagen I density, particularly evident within the first 14 days after injury.
9 citations
,
July 2020 in “Cell Proliferation” In this study, EREG promoted hair growth by activating specific receptors in cell and animal models, indicating it may be a potential treatment for hair loss.
9 citations
,
October 2017 in “Translational pediatrics” This review examines the skin manifestations of various endocrine disorders, highlighting their underlying pathophysiology and impact on an individual's health and quality of life, without reporting new research findings.
9 citations
,
May 2014 in “Journal of Cardiovascular Development and Disease” This review discusses the role of Wnt signaling in cardiac development and explores attempts to modulate it for improving heart function after ischemic injury, but reports no new experimental results.
8 citations
,
June 2025 in “Stem Cell Research & Therapy” This review discusses the potential of exosome therapy for treating diabetic peripheral neuropathy but highlights the need for more robust preclinical trials before clinical application.
8 citations
,
January 2025 in “JADA Foundational Science” This review discusses the state-of-the-art in photobiomodulation therapy for oral and dental applications and emphasizes the need for education, training, and addressing logistical issues for its routine use.
8 citations
,
July 2022 in “BMC neuroscience” In this study, intranasal delivery of hair follicle-derived stem cells improved neurological function and reduced brain damage in a rat model of ischemic stroke.
8 citations
,
January 2021 in “Advances in Traditional Medicine” In this study, black tea kombucha with and without MSM significantly improved hair density and length in mice, suggesting its potential as a natural hair regrowth treatment.
8 citations
,
January 2016 in “Cells tissues organs” This study found that chemical sympathectomy inhibited hair follicle growth in mice, suggesting that sympathetic nerves may regulate keratinocyte behavior to promote hair growth.
7 citations
,
June 2022 in “Frontiers in Medicine” This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.
6 citations
,
July 2023 in “Diabetology” This study in an animal model found that Rigenera® technology's use of autologous micrografts improved wound healing in diabetic rats by increasing factors like VEGF-A, IL4, and IL10 while reducing TNF-α and oxidative stress.
6 citations
,
April 2022 in “Biomedicine & pharmacotherapy” This review discusses the potential of using triads of repositioned medicines targeting multiple pathogenic mechanisms to prevent or delay retina degeneration, but reports no new results.
6 citations
,
October 2014 in “International Journal of Molecular Sciences” Tanshinone IIA helps protect tissue from low oxygen damage by activating certain cell pathways.
5 citations
,
June 2025 in “Journal of Functional Biomaterials” This study explored recent advancements in 3D bioprinting for head and neck defects, highlighting how bioinks and scaffolds may improve treatment customization and functionality by mimicking native tissue features. The research also examined challenges like biocompatibility and regulatory requirements on the path to clinical use.
5 citations
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May 2024 in “BMC Biotechnology” This study found that using three-dimensional cell culture with Matrigel enhances the biological function and stemness of stem cells, leading to improved soft tissue repair and healing by activating the host microenvironment and autologous stem cells.