TLDR Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.
The document from October 2017 emphasized the importance of fertility counseling and preservation in pediatric endocrinology, particularly for patients undergoing treatments that could potentially harm their future fertility. It highlighted the need for early and ongoing discussions about fertility with patients and their families, and the role of multidisciplinary teams in managing these cases. The paper outlined various fertility preservation options for both males and females, and reviewed pediatric populations at risk for infertility, such as those undergoing oncologic therapy, hematopoietic stem cell transplantation, and those with gender dysphoria. It also discussed disorders/differences of sex development (DSD), and other causes of gonadal dysfunction, such as genetic/metabolic conditions and autoimmune ovarian insufficiency. The document concluded that pediatric endocrinologists need to be educated and trained in addressing these issues, as timely fertility counseling results in higher rates of fertility preservation and improved satisfaction among patients and families.
855 citations,
June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
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14 citations,
February 2016 in “Journal of Obstetrics and Gynaecology Research” Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.
2 citations,
July 2012 in “Journal of Pediatric and Adolescent Gynecology” A 12-year-old girl with very high testosterone and insulin resistance improved with birth control pills, suggesting PCOS can cause high testosterone without tumors.
3 citations,
January 2012 in “Hanyang Medical Reviews” The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
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67 citations,
February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
85 citations,
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1 citations,
April 1993 in “Problemy e̊ndokrinologii” Spironolactone effectively reduces symptoms of hyperandrogenism like hirsutism and acne.
