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GlossaryBone Marrow Transplantation (Hematopoietic Stem Cell Transplantation)

medical procedure replacing damaged bone marrow with healthy stem cells

Bone Marrow Transplantation (BMT), also known as Hematopoietic Stem Cell Transplantation (HSCT), is a medical procedure used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. This treatment is often used for patients with certain cancers like leukemia or lymphoma, as well as other blood or immune system disorders. The healthy stem cells can come from the patient (autologous transplant) or a donor (allogeneic transplant).

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research Complete Resolution of Alopecia Totalis Following Chemotherapy Treatment for B-Cell Acute Lymphoblastic Leukemia

March 2022 in “Authorea (Authorea)”

Chemotherapy for leukemia led to full hair regrowth in a child with alopecia totalis.

research A Case of Red Lunulae After Hematopoietic Stem Cell Transplantation

May 2018 in “European Journal of Dermatology”

Adjusting the medication tacrolimus resolved a boy's red nail beds after a stem cell transplant.

research Fertility Counseling and Preservation: Considerations for the Pediatric Endocrinologist

9 citations , October 2017 in “Translational pediatrics”

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

Rapid Full Engraftment and Successful Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Conditioning in Omenn Syndrome

research Rapid Full Engraftment and Successful Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Conditioning in Omenn Syndrome

8 citations , August 2009 in “Pediatric transplantation”

A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.

research Advances in Genetic and Molecular Understanding of Omenn Syndrome: Implications for the Future

2 citations , May 2018 in “Expert opinion on orphan drugs”

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

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community Painkillers May Block Minoxidil

in Research/Science 15 upvotes 1 year ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.