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GlossaryBone Marrow Transplantation (Hematopoietic Stem Cell Transplantation)

medical procedure replacing damaged bone marrow with healthy stem cells

Bone Marrow Transplantation (BMT), also known as Hematopoietic Stem Cell Transplantation (HSCT), is a medical procedure used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. This treatment is often used for patients with certain cancers like leukemia or lymphoma, as well as other blood or immune system disorders. The healthy stem cells can come from the patient (autologous transplant) or a donor (allogeneic transplant).

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research Six Cases of Permanent Alopecia After Various Conditioning Regimens Commonly Used in Hematopoietic Stem Cell Transplantation

40 citations , September 2007 in “Bone marrow transplantation”

Certain chemotherapy drugs can cause permanent hair loss in stem cell transplant patients.

Rapid Full Engraftment and Successful Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Conditioning in Omenn Syndrome

research Rapid Full Engraftment and Successful Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Conditioning in Omenn Syndrome

8 citations , August 2009 in “Pediatric transplantation”

A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.

research Permanent Chemotherapy-Induced Alopecia After Hematopoietic Stem Cell Transplantation Treated With Low-Dose Oral Minoxidil

4 citations , February 2022 in “JAAD case reports”

The document concludes that low-dose oral minoxidil successfully regrew hair in a patient with permanent hair loss after chemotherapy and stem cell transplant.

Clinical and Histopathological Features of Hair Loss in 17 Japanese Patients With Hematologic Disorders Following Hematopoietic Stem Cell Transplantation and Chemotherapy: A Case Series

research Clinical and Histopathological Features of Hair Loss in 17 Japanese Patients With Hematologic Disorders Following Hematopoietic Stem Cell Transplantation and Chemotherapy: A Case Series

September 2025 in “PubMed”

Hair miniaturization is the main cause of long-term hair loss after stem cell transplantation and chemotherapy, and treatments like topical minoxidil can help improve hair volume.

research A Case of Lupus Miliaris Disseminatus Faciei After Allogeneic Hematopoietic Stem Cell Transplantation

1 citations , August 2019 in “Chinese Medical Journal”

A man developed facial skin lesions after a stem cell transplant, which improved with specific treatments.

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community Painkillers May Block Minoxidil

in Research/Science 13 upvotes 7 months ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.