A Case of Lupus Miliaris Disseminatus Faciei After Allogeneic Hematopoietic Stem Cell Transplantation
August 2019
in “
Chinese Medical Journal
”
Studysummary This case report describes a 43-year-old man who developed lupus miliaris disseminatus faciei after discontinuation of cyclosporine A post-stem cell transplantation, successfully treated with oral isotretinoin and topical tacrolimus. Our plain-language summary of this paper — not a Tressless recommendation.
A 43-year-old man developed lupus miliaris disseminatus faciei (LMDF) after discontinuing cyclosporine A following an allogeneic hematopoietic stem cell transplantation. The patient presented with multiple reddish-brown papules on his face, which were confirmed through histopathological analysis to be epithelioid cell granulomas with caseation necrosis. Despite negative tuberculosis tests, the condition was treated effectively with a 6-month regimen of oral isotretinoin and topical tacrolimus, resulting in significant improvement. The case suggested that immunological changes post-transplantation might contribute to LMDF pathogenesis.
