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Glossary Granulomas

small clusters of immune cells forming to isolate foreign substances

Granulomas are small areas of inflammation caused by the immune system's attempt to isolate substances it perceives as foreign but cannot eliminate. They often form in response to infections, such as tuberculosis, or inflammatory conditions, like sarcoidosis, and are characterized by a collection of immune cells, primarily macrophages, that transform into a more specialized form called epithelioid cells.

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research Management of Visible Granulomas Following Periorbital Injection of Poly-L-Lactic Acid

49 citations , July 2007 in “Ophthalmic Plastic and Reconstructive Surgery”

This report describes a case of granulomatous reaction to injectable poly-L-lactic acid in the periorbital area and suggests surgical excision as an effective treatment for persistent nodules.

research Granulomatous pigmented purpuric dermatosis containing Propionibacterium acnes

8 citations , July 2018 in “European Journal of Dermatology”

A medication may help with hair growth in psoriasis, and a skin condition might be linked to a specific bacteria.

research Lichen Planopilaris With Foreign-Body Granuloma

5 citations , April 2014 in “The American Journal of Dermatopathology”

This article reports on a typical case of lichen planopilaris with foreign-body granulomas around hair shaft material, suggesting these may be an additional criterion for diagnosing late-stage LPP/FFA.

research Caution with Hair Dye: Foreign Body Skull Erosive Granuloma from Exogenous Hair Pigmentation

3 citations , May 2020 in “Annals of the Academy of Medicine Singapore”

Hair dye can cause serious scalp issues, including skull erosion.

research Delayed granulomatous eruption of the nose associated with ruxolitinib

2 citations , May 2020 in “JAAD case reports”

This review discusses the potential role of JAK inhibitors, like ruxolitinib, as emerging therapeutic agents in dermatology, but reports no new clinical results.

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