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    Glossary Granulomatous Inflammation

    immune system forms cell clusters to isolate persistent irritants

    Granulomatous inflammation is a type of chronic inflammation where the immune system forms small clusters of cells called granulomas to wall off substances it perceives as foreign but cannot eliminate. These granulomas are often seen in conditions like tuberculosis, sarcoidosis, and certain fungal infections, and they help contain the spread of the offending agent while the body attempts to neutralize it.

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      Granulomatous Inflammation in Alopecia Areata: A Diagnostic Pitfall

      research Granulomatous Inflammation in Alopecia Areata: A Diagnostic Pitfall

      June 2026 in “Indian Dermatology Online Journal”
      This study observed a rare case of alopecia areata with granulomatous inflammation, successfully treated with intralesional triamcinolone, leading to complete hair regrowth within two months, highlighting the need for careful diagnosis to distinguish it from other granulomatous alopecias.

      research Granulomatous Alopecia Areata: A Rare Report With a Review

      June 2025 in “American Journal of Dermatopathology”
      This case report describes a rare instance of sarcoidal granulomatous alopecia areata in a 42-year-old man, with histopathological findings suggesting inflammation but ruling out causes like tuberculosis and syphilis, resulting in treatment with tofacitinib.
      Granulomatous Alopecia Areata

      research BH12 Granulomatous alopecia areata

      June 2023 in “British journal of dermatology/British journal of dermatology, Supplement”
      In this report, a 46-year-old woman's sudden diffuse hair loss was diagnosed as granulomatous alopecia areata, with spontaneous hair regrowth observed after two months. This case highlights that granulomatous inflammation should not exclude the diagnosis of alopecia areata, emphasizing the importance of clinicopathological correlation.