May 2019 in “Eurasian Journal of Biosciences” Fenugreek aqueous extract is more effective against acne bacteria than the alcoholic extract.
78 citations
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June 2021 in “Dermatology and Therapy” The document discussed advancements in acne treatment, emphasizing targeted therapies based on the pathogenesis of acne. It highlighted the role of androgen-mediated sebogenesis, hyperkeratinization, Cutibacterium acnes colonization, and inflammation in acne development. Recent research suggested that biological antibodies targeting interleukins (IL-1β, IL-17, IL-23) and tumor necrosis factor alpha (TNFα) could offer new treatment options for severe acne. The study also noted the importance of insulin growth factor 1 (IGF-1) in sebocyte activity and the potential of microbiome research in developing future therapies. Acne scars, both atrophic and hypertrophic, were linked to genetic, systemic, local, and lifestyle factors, with pro-inflammatory cytokines playing a key role in hypertrophic scar formation. Limited treatments for keloid scarring included surgery and radiotherapy, but targeting cytokines like TGFβ, IL-6, and MMP with biological antibodies might prevent and treat scars. The document concluded that future acne treatments should focus on aggressive management during the acute inflammatory phase to prevent scarring and other sequelae, while also addressing established acne-induced conditions.
7 citations
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February 2006 in “Clinical and Experimental Dermatology” Using anabolic steroids 'Sus' and 'Deca' for bodybuilding caused severe acne in a man.
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July 2023 in “Scientific Reports” Wearing a hijab changes the common bacteria and fungi on the scalp, possibly affecting skin health.
January 2022 in “Drug Delivery” The aloe ferox gel with finasteride and oregano oil may effectively treat alopecia.