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GlossaryCutibacterium acnes (Propionibacterium)

bacteria on skin contributing to acne development

Cutibacterium acnes, formerly known as Propionibacterium acnes, is a type of bacteria commonly found on human skin. It plays a role in the development of acne by contributing to inflammation and infection within hair follicles. While it is a normal part of the skin's microbiome, an overgrowth or imbalance can lead to skin issues.

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research Understanding the Role of Propionibacterium Acnes in Acne Vulgaris: The Critical Importance of Skin Sampling Methodologies

59 citations, October 2016 in “Clinics in dermatology”

Precise skin sampling is crucial to understand the role of P. acnes in acne.

research Pattern of Tissue Invasion by Propionibacterium Acnes in Acne Vulgaris

35 citations, March 2012 in “Journal of dermatological science”

The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.

research Is Propionibacterium Acnes Associated With Hair Casts And Alopecia?

19 citations, January 2012 in “International Journal of Trichology”

Propionibacterium acnes might be linked to hair casts and possibly alopecia.

research Granulomatous Pigmented Purpuric Dermatosis Containing Propionibacterium Acnes

8 citations, July 2018 in “European Journal of Dermatology”

A medication may help with hair growth in psoriasis, and a skin condition might be linked to a specific bacteria.

research The Potential of Clausena Anisata (Willd.) Hook.f. ex Benth Against Propionibacterium Acnes

7 citations, October 2018 in “South African journal of botany”

Clausena anisata may be effective in treating acne due to its ability to fight bacteria, reduce inflammation, and possibly lower sebum production.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 2 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 62 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.