Head And Neck 3D Bioprinting: A Review On Recent Advancements In Soft Tissue 3D Bioprinting And Medical Applications

June 2025 in “ Journal of Functional Biomaterials ”

Iosif-Aliodor Timofticiuc, Ana Căruntu, Christiana Diana Maria Dragosloveanu, Andreea-Elena Scheau, Ioana Anca Bădărău, Argyrios Periferakis, Şerban Dragosloveanu, Andreea Cristiana Didilescu, Constantin Căruntu, Cristian Scheau

TLDR 3D bioprinting offers new ways to treat head and neck defects with bioinks that mimic natural tissues.

Recent advancements in 3D bioprinting present innovative solutions for treating head and neck defects by using bioinks that mimic the natural structure and function of soft tissues. These developments allow for precise model construction and improved scaffold control, addressing issues like donor availability and immune response associated with traditional treatments. The paper reviews the use of natural and synthetic bioinks to replicate native tissue features, discusses customization for anatomical precision, and examines regulatory and biocompatibility challenges for clinical application.

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