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    Glossary Post-Transcriptional Gene Silencing

    cells inhibit gene expression after RNA is made

    Post-Transcriptional Gene Silencing (PTGS) is a cellular process where the expression of specific genes is inhibited after the DNA has been transcribed into RNA. This is often achieved through mechanisms like RNA interference (RNAi), where small RNA molecules bind to the messenger RNA (mRNA) and prevent it from being translated into proteins. This process is crucial for regulating gene expression and maintaining cellular function.

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    1. Importance of microRNAs in skin morphogenesis and diseases. PubMed · 2008 · 70 citations
    2. LncRNA-599547 contributes the inductive property of dermal papilla cells in cashmere goat through miR-15b-5p/Wnt10b axis Animal biotechnology · 2020 · 7 citations
    3. A computationally inferred regulatory heart aging model including post-transcriptional regulations 2016 · 1 citations
    4. From gene to therapy in spinal and bulbar muscular atrophy: Are we there yet? Molecular and Cellular Endocrinology · 2017 · 17 citations
    5. Dicer- and BSC-dependent miRNAs during murine anagen development bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    6. Reshaped DNA methylation cooperating with homoeolog‐divergent expression promotes improved root traits in synthesized tetraploid wheat New phytologist · 2024
    7. UDP-GlcNAc-1-Phosphotransferase Is a Clinically Important Regulator of Human and Mouse Hair Pigmentation Journal of Investigative Dermatology · 2021 · 10 citations
    8. LncRNA018392 promotes the proliferation of Liaoning cashmere goat skin fibroblasts by upregulating CSF1R through binding to SPI1 Molecular Biology Reports · 2024 · 3 citations
    9. Is There a Histone Code for Cellular Quiescence? Frontiers in Cell and Developmental Biology · 2021 · 27 citations
    10. Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia PLoS ONE · 2007 · 77 citations
    11. SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation Cellular and Molecular Immunology · 2026
    12. ATP-dependent chromatin remodeling during mammalian development Development · 2016 · 182 citations
    13. Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear Neuroscience Bulletin · 2023 · 26 citations
    14. Olfactory receptor OR2AT4 regulates human hair growth Nature Communications · 2018 · 82 citations
    15. Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle ˜The œFASEB journal · 2010 · 149 citations
    16. Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75 Journal of Investigative Dermatology · 2015 · 6 citations
    17. p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis Journal of Investigative Dermatology · 2015 · 19 citations
    18. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    19. Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling Journal of Biological Chemistry · 2003 · 215 citations
    20. Study of seed hair growth in Populus tomentosa, an important character of female floral bud development BMC genomics · 2014 · 20 citations
    21. The molecular anatomy of cashmere goat hair follicle during cytodifferentiation stage BMC Genomics · 2024
    22. Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein 2023
    23. Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle PloS one · 2015 · 31 citations
    24. Double Knockdown of the Androgen Receptor Target Genes DKK1 and SFRP1 Does Not Potentiate the Hair Growth-Promoting Effect of SFRP1 Silencing in Healthy Human Hair Follicles Ex Vivo International Journal of Molecular Sciences · 2026
    25. Epigenetic control of skin and hair regeneration after wounding Experimental Dermatology · 2014 · 36 citations
    26. Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells Development · 2024 · 4 citations
    27. Regulation of feather follicle development and Msx2 gene SNP degradation in Hungarian white goose BMC Genomics · 2022 · 1 citations
    28. Gene expression profiling of intestinal regeneration in the sea cucumber BMC Genomics · 2009 · 106 citations
    29. From Follicle Cell Differentiation and Structure to Chorion Biogenesis in Insects: Cellular Mechanisms, Gene Regulation, Biochemical Composition and Structural Diversity Insects · 2026
    30. The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development 2016 · 16 citations