TLDR Hair shaft miR-221 levels can help detect malignant melanoma.
The study investigated the potential of hair shaft miR-221 levels as a marker for malignant melanoma (MM). It found that miR-221 levels in the hair shaft were significantly higher in MM patients compared to controls. The detection rates of elevated hair shaft miR-221 were similar to those of serum 5-S-CD, a commonly used MM marker. This suggested that measuring hair shaft miR-221 could be a valuable, non-invasive method for MM detection, providing new insights into the relationship between miR-221 and MM. This was the first report to explore hair shaft miR-221 levels in MM patients.
27 citations,
October 2013 in “Experimental dermatology” Scleroderma patients have lower hair miR-29a levels.
39 citations,
July 2013 in “Journal of dermatological science” Hair microRNAs could be effective biomarkers for diagnosing scleroderma.
39 citations,
July 2013 in “Journal of dermatological science” Hair microRNAs could be effective biomarkers for diagnosing scleroderma.
37 citations,
November 2017 in “Medical Sciences” Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
9 citations,
July 2020 in “Experimental Dermatology” Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
16 citations,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
