Bioengineered Polyester Nanoparticles for the Synergistic Treatment of Androgenic Alopecia via the Suppression of 5α-Reductase and Knockdown of Androgen Receptor

    October 2022 in “ Frontiers in Bioengineering and Biotechnology ”
    Xiangru Chen, Peiyu Yan, Wenqiang Zhang … Jinlan Jiang
    Studysummary This study demonstrated that in a mouse model of androgenic alopecia, PLGA-DUT/siAR@DPCM nanoparticles effectively delivered drugs to hair follicles, suppressed androgen-related targets, promoted cell proliferation, and showed significant therapeutic effects with minimal adverse effects, suggesting their potential for clinical application.
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    Research cited in this study 21

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    1. Bioengineered Polyester Nanoparticles for the Synergistic Treatment of Androgenic Alopecia via the Suppression of 5α-Reductase and Knockdown of Androgen Receptor Frontiers in Bioengineering and Biotechnology · 2022