31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
42 citations,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
29 citations,
December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
September 2023 in “Journal of microbiology and biotechnology” A type of collagen helps hair grow by boosting cell growth and activating a specific hair growth pathway.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
1 citations,
January 2022 in “Stem cell biology and regenerative medicine” New methods to test hair growth treatments have been developed.
64 citations,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
24 citations,
October 2017 in “Scientific reports” Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.
3 citations,
May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
179 citations,
April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
9 citations,
January 2015 in “Medical hypotheses” TCDD disrupts skin stem cells, causing skin issues like chloracne.
20 citations,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
9 citations,
July 2018 in “European journal of dermatology/EJD. European journal of dermatology” Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
35 citations,
January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
135 citations,
December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
March 2020 in “Central European Journal of Biology” The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
December 2024 in “International Journal of Molecular Sciences” Human umbilical cord stem cell vesicles may help treat aging and related diseases.
8 citations,
July 2022 in “BMC neuroscience” Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
41 citations,
March 2019 in “Circulation research” Adult stem cells are effective and ethically acceptable for treating various diseases.
25 citations,
January 2015 in “World journal of stem cells” Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
15 citations,
January 2018 in “Biomedical Reports” Exosomes are important for skin health and could help diagnose and treat skin diseases.
October 2020 in “Stem cells” The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
25 citations,
November 2017 in “Molecular Medicine Reports” PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.
3 citations,
May 2013 in “International journal of molecular sciences” Epidermal stem cells show promise for treating orthopedic injuries and diseases.
15 citations,
January 2015 in “Stem cells international” Human hair follicle stem cells can be turned into red blood cells.
January 2025 in “Frontiers in Cell and Developmental Biology” Hox proteins help maintain keratinocyte identity by regulating miRNA expression.
23 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
138 citations,
June 2019 in “Stem Cells and Development” Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
58 citations,
August 2015 in “The Indonesian Biomedical Journal” Different types of stem cells help maintain and heal skin.