489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
474 citations,
January 2012 in “Chemistry & biology” Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
48 citations,
April 2010 in “Journal of the European Academy of Dermatology and Venereology” Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
2 citations,
August 2022 in “Emergency medicine international” Keloid skin disorder involves abnormal fibroblast activation and immune response, linked to a group of genes including FGF11.
152 citations,
March 1988 in “Journal of The American Academy of Dermatology” Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.
4 citations,
June 2021 in “Wounds-a Compendium of Clinical Research and Practice” Chronic scalp lesions with crusts and pus that heal with strong topical steroids suggest Erosive Pustular Dermatosis, confirmed by biopsy showing specific immune cells.
May 2022 in “Liver transplantation” The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
71 citations,
May 2019 in “Rheumatology” Tph cells are linked to the severity of systemic lupus erythematosus.
1 citations,
October 2022 in “Biomedicines” Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
June 2017 in “The Medical Journal of Australia” The man's rash, hair loss, and vision issues were due to syphilis, not CMV.
June 2022 in “Mayo Clinic Proceedings” The man was diagnosed with stage III multiple myeloma and treated to improve kidney function.
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July 2015 in “Journal of Feline Medicine and Surgery Open Reports” A cat with hair loss and illness was found to have cancer spread from its colon.
The combination therapy effectively improved acne keloidalis nuchae.
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April 2014 in “Drugs” Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
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September 2016 in “Dermatology and Therapy” Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.
53 citations,
May 1995 in “Journal of The American Academy of Dermatology” Syphilis can cause hair loss that looks like other conditions, but it improves with treatment.
45 citations,
December 2014 in “Journal of the European Academy of Dermatology and Venereology” Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.
37 citations,
May 1999 in “Australasian Journal of Dermatology” Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
14 citations,
May 2013 in “Emerging infectious diseases” Cryptococcus gattii can remain dormant in animals for over 8 years.
11 citations,
September 1999 in “Journal of the European Academy of Dermatology and Venereology” Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.
7 citations,
January 2011 in “Journal of The American Academy of Dermatology” Most women with hyperandrogenism first show acne, and skin conditions like hirsutism and acanthosis nigricans are good indicators of the condition.
January 2011 in “Journal of The American Academy of Dermatology” Treating generalized granuloma annulare is difficult, with PUVA being the most effective option, but relapses are common.
January 2011 in “Journal of The American Academy of Dermatology” Two patients had a rare combination of red skin spots and white scaly skin lesions not on the genitals.
50 citations,
July 2021 in “Nature Communications” The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
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January 1989 in “Toxicologic Pathology” Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.
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December 2004 in “Seminars in oncology” Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.
16 citations,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
11 citations,
December 2010 in “Archives of Dermatology” A man with rare skin changes on his fingers was diagnosed with multiple myeloma-linked amyloidosis.
11 citations,
January 1993 in “Dermatology” EMS and EF both show similar skin and fascia changes, but EMS has more severe symptoms and nerve inflammation.
9 citations,
May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.