Beneficial Effects of Finasteride on Hepatic and Pulmonary Immune Response After Trauma Hemorrhage in Mice
April 2015
in “
Cytokine
”
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Studysummary This study found that finasteride may improve pulmonary and hepatic immune responses in mice when administered after major trauma and hemorrhage. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigated the effects of finasteride on the immune response after trauma hemorrhage in male mice. The results showed that finasteride treatment led to reduced levels of pro-inflammatory mediators, reduced cytokine secretion, and reduced organ damage. The study suggests that finasteride may have beneficial effects on the immune response after trauma hemorrhage and could improve posttraumatic immune response and outcome after multiple trauma. Further research is needed to determine the efficacy of finasteride in a clinical setting.