1 citations
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July 2019 in “Journal of the Korean Society of Food Science and Nutrition” This study found that platycodon ethanol extract showed potential as a natural ingredient for hair loss prevention by increasing radical scavenging ability, inhibiting inflammation, and affecting DHT generation in laboratory experiments.
7 citations
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August 2020 in “Majalah Farmasetika” This review concluded that a herbal hair tonic formulated with 2.5% green tea leaf extract, in combination with specific solvents and additives, showed the best properties for stimulating hair growth.
September 2025 in “Jurnal Ilmu Kedokteran dan Kesehatan Indonesia” The study found that a pomade containing bay leaf extract significantly promoted hair growth in New Zealand White rabbits, with the 30% extract formula demonstrating the highest growth compared to lower concentrations and a control without extract.
1 citations
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August 2016 in “Hanbang an'i'bi'in'hu pibu'gwa haghoeji” In this study using lab models, YangHyulEum Gami-Bang (YHEG) was associated with promoting hair growth and inhibiting factors that contribute to hair loss.
12 citations
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January 1988 in “YAKUGAKU ZASSHI” This study found that Polygonum multiflorum and Panax japonicum extracts could promote hair regrowth in mice, suggesting potential use as hair tonics.
August 2025 in “Y HOC TP HO CHI MINH” In this study on Swiss albino mice, researchers reported that perilla leaf extract stimulated hair growth similarly to minoxidil, counteracting hair loss induced by testosterone injections.
108 citations
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November 2006 in “Phytomedicine” This study found that EGCG from green tea may stimulate human hair growth by promoting the proliferation and anti-apoptotic activity in dermal papilla cells.
August 2024 in “Cosmetics” This study reported that peanut callus extract, rich in resveratrol, significantly stimulated hair growth and reduced hair loss in an in vitro model and a clinical trial, showing promise as a cosmetic bioactive ingredient.
5 citations
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July 2017 in “Molecular Medicine Reports” This study observed that ethanol extracts of Lygodium japonicum spores significantly reduced inflammatory responses in LPS-stimulated murine macrophages in vitro by negatively regulating p38 MAPK and NF-κB.
4 citations
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February 2025 in “Nutrients” This randomized controlled trial found that consuming *Gynostemma pentaphyllum* extract significantly improved hair elasticity, density, and diameter over 24 weeks without severe adverse events, suggesting it as a safe functional food ingredient for hair health improvement.
3 citations
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January 2003 This study found that SPELA 707, a herbal extract mixture, enhanced hair density and promoted hair growth by converting hair into the anagen phase in individuals with androgenetic alopecia and C3H mice.
2 citations
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January 2017 in “Plant” This study found that in vitro extracts of Glycyrrhiza glabra root are strong antioxidants, particularly in ethanolic form, and contain secondary metabolites, but only showed mild antibacterial activity.
August 2019 in “Journal of the American Academy of Dermatology” Ginseng and Albizia extracts help prevent hair thinning with age.
1 citations
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July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Ashwagandha-derived nanovesicles increased cell proliferation, angiogenesis, and growth factor expression in vitro, suggesting they may have potential as a plant-based alternative or complement to current therapies for hair and skin conditions.
January 2016 in “Journal of chemical and pharmaceutical research” The study reported that both ethanol and water extracts of pakis munding roots significantly promoted hair growth in male rabbits, showing better results than the marketed hair growth drug minoxidil.
January 2024 in “Pharmacokinetics and Pharmacodynamics” This review discusses peptide "biogenic stimulants" from human placenta extracts, highlighting their potential wide-ranging clinical applications across multiple diseases, and reports no new clinical results.
April 2024 in “Journal of pharmacy & pharmacognosy research” This study used in silico analysis to identify 4-[2-(4-nitrophenyl)ethylcarbamoyl]benzenesulfonyl as a potential inhibitor of the EGFR mutant associated with NSCLC, highlighting the need for further in vitro and in vivo validation.
24 citations
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January 2014 in “The American Journal of Chinese Medicine” This review compiles data on Platycladus orientalis leaves, noting their diverse pharmacological activities and advocating for more research to clarify their traditional blood-cooling and hematostatic uses.
In this study, a hair tonic formulation with bean leaf juice increased hair growth in male rabbits, with concentration-dependent improvements in hair length and weight compared to a control.
January 2025 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” This study found that EGCG, a compound from green tea, may enhance the proliferation and antioxidant activity of dermal papilla cells by upregulating VEGFA expression, potentially aiding hair follicle growth.
1 citations
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September 2025 in “Molecules” This study comparatively evaluated different extraction techniques for Schinus terebinthifolius Raddi leaf extracts and found that conventional extraction with ethanol yielded the highest antioxidant activity and beneficial effects on skin cell viability, supporting its potential use in sustainable cosmeceutical formulations targeting skin aging.
16 citations
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April 2017 in “Journal of Cosmetic Dermatology” This study found that fig leaf extract significantly downregulated inflammatory and androgenic gene expression in vitro, suggesting potential topical benefits for certain skin disorders.
December 2023 in “Polish Journal of Chemical Technology” This study found that Ajuga reptans leaf and root extracts, when incorporated into cosmetic products, improved skin hydration, elasticity, pore size, hyperpigmentation, and wrinkle depth.
6 citations
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August 2022 in “Journal of Herbal Medicine” In this study, mangosteen pericarp water extract was found to significantly promote hair dermal papilla cell proliferation and enhance melanin synthesis in vitro, surpassing known melanogenic agents such as α-melanocyte stimulating hormone and forskolin in potency.
In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.
19 citations
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January 2012 in “Biomolecules & Therapeutics” This study found that Grateloupia elliptica extract may help treat hair loss by promoting dermal papilla cell proliferation, inhibiting 5α-reductase, and reducing inflammation in various cell types.
This study found that ethanolic extract and fractions of Ceiba leaf tonic may enhance rabbit hair growth similarly to 2% minoxidil.
3 citations
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November 2022 in “Molecules/Molecules online/Molecules annual” This study found that ingesting Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. extract promoted hair regrowth and follicle maturation in mice by enhancing cytoprotective effects and growth factor expression.
This study found that bitter melon leaf extract, particularly at a 10% concentration, promoted hair growth in male rabbits, outperforming the effect of a 2% minoxidil solution.